SynthesisFrontiers in oncology2026
Living alone and mortality risk in cancer patients: a systematic review and meta-analysis.
Synthesis in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Living alone has become increasingly prevalent across the globe, but its association with all-cause mortality among cancer patients remains unclear. This systematic review and meta-analysis evaluated the relationship between living alone and all-cause mortality risk in cancer patients. Methods: A comprehensive search of PubMed, Embase, Cochrane Library, and Ovid Medline was performed up to July 10, 2026. We included cohort studies that reported adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause mortality comparing cancer patients living alone with those not living alone. Pooled estimates were calculated using an inverse-variance random-effects model. Results: Twenty-one cohort studies comprising 2,497,397 cancer patients (55.6% female) were included. Compared with patients not living alone, those living alone had a significantly higher risk of all-cause mortality (HR = 1.22, 95% CI: 1.13-1.32). In sex-specific analyses, the pooled HR was 1.34 (95% CI: 1.23-1.45) for men and 1.15(95% CI: 1.00-1.32) for women, with no statistically significant subgroup difference (p = 0.06), indicating no clear sex difference in this association. Conclusion: Living alone is associated with increased all-cause mortality in cancer patients, with no apparent sex difference. Systematic Review Registration: https://inplasy.com/inplasy-2024-10-0051/, identifier INPLASY2024100051.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.