Evidence map›Paper›PMID 42643079›Full record

ArticleThe Journal of experimental biology2026

Gills are not the primary site of gas exchange in the suspension-feeding hemichordate Protoglossus graveolens.

Michael A Sackville, Christopher B Cameron, Colin J Brauner

Abstract read
In one paragraph

Article in The Journal of experimental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael A SackvilleDepartment of Biology, University of Ottawa, Ottawa, ON, Canada, K1N 6N5.ORCID 0000-0001-8206-6836
Christopher B CameronDépartement de Sciences Biologiques, Université de Montréal, Montréal, PQ, Canada, H3C 3J7.
Colin J BraunerDepartment of Zoology, University of British Columbia, Vancouver, BC, Canada, V6T 1Z4.

Funding

Natural Sciences and Engineering Research Council of Canada 1283784Natural Sciences and Engineering Research Council of Canada 2018-04172University of Ottawa
6 · The paper itself

Abstract

The gills are hypothesized to play a key role in early vertebrate evolution by replacing the skin as the primary site of gas exchange. In this scenario, water flow across the gills for suspension feeding was coopted for gas exchange in stem vertebrates, facilitating the evolution of larger, active fishes. This is supported by a stem-vertebrate origin for structures increasing gill capacity for gas exchange. However, these structures might have enhanced an already dominant capacity at ancestral deuterostome gills. To test this, we characterized gill function in the suspension-feeding hemichordate Protoglossus graveolens. We measured oxygen uptake and ammonia excretion in whole worms and worm halves with or without gills at 10°C and 20°C to stimulate gill recruitment. Gills did not enhance oxygen uptake or ammonia excretion, suggesting they are not a primary site of gas exchange. This provides critical functional support for the long-hypothesized vertebrate origin of gills as the primary gas exchange organ.

Indexed as

Chordata, NonvertebrateGillsAmmoniaAnimalsBiological EvolutionOxygenOxygen ConsumptionAmmoniaOxygenDeuterostomePharyngeal gill slitsVertebrate evolution

Identifiers

PMID42643079
PMCPMC13615691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.