Evidence map›Paper›PMID 42642896›Full record

ArticlePhysiological reports2026

Intratracheal interleukin-10 administration reduces acute lung injury induced by sulfur dioxide exposure in mice.

Amy J Nelson, Todd A Wyatt, Bradley W Richmond, Belinda Diaz, Angela M Gleason, Michael J Duryee, Geoffrey M Thiele, Ted R Mikuls, Jill A Poole

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amy J NelsonDivision of Allergy & Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Todd A WyattDivision of Pulmonary, Critical Care & Sleep, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Bradley W RichmondDivision of Allergy, Pulmonary, and Critical Care, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Belinda DiazDivision of Allergy & Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Angela M GleasonDivision of Allergy & Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Michael J DuryeeVeterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska, USA.
Geoffrey M ThieleVeterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska, USA.
Ted R MikulsVeterans Affairs Nebraska-Western Iowa Health Care System, Research Service, Omaha, Nebraska, USA.
Jill A PooleDivision of Allergy & Immunology, University of Nebraska Medical Center, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0002-6236-2563

Funding

Tracking and Evaluation CoreU54GM115458 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI ZHANG, YING · 2016 to 2025
$42.8M
BLRD VA I01 BX005886BLRD VA IK6 BX003781BLRD VA IK6 BX005962CSRD VA I01 CX002995HHS | CDC | National Institute for Occupational Safety and Health (NIOSH) R01OH012045HHS | NIH | National Institute of General Medical Sciences (NIGMS) 2U54GM115458NIGMS NIH HHS U54 GM115458NIOSH CDC HHS R01 OH012045Rheumatology Research Foundation (RRF)U.S. Department of Defense (DOD) PR200793U.S. Department of Veterans Affairs (VA) I01 BX005886U.S. Department of Veterans Affairs (VA) I01 CX002995U.S. Department of Veterans Affairs (VA) IK6 BX005962
6 · The paper itself

Abstract

Therapies capable of reducing acute high-consequence airborne chemical exposure-induced lung disease are lacking. This study seeks to determine the therapeutic potential of interleukin (IL)-10 administered following acute sulfur dioxide (SO

Indexed as

Acute Lung InjuryInterleukin-10Sulfur DioxideAnimalsFemaleLungMaleMiceMice, Inbred C57BLIL10 protein, mouseInterleukin-10Sulfur Dioxidechemicalinflammationinjurylungtreatment

Identifiers

PMID42642896
PMCPMC13507516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.