Evidence map›Paper›PMID 42642770›Full record

ArticleTrials2026

Cast Or ePineural Suture for digital nerve injuries (COPS): study protocol for a randomized controlled trial.

Carin Carlsson, Johanna von Kieseritzky, Marianne Arner, Cecilia Mellstrand Navarro

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05536609 (Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05536609 narecruitingnot on this map

Cast Or ePineural Suture for Digital Nerve Injuries - a Randomised Controlled Study

TypeinterventionalSponsorKarolinska InstitutetRan2022 to 2031Enrolled166ConditionsDigital Nerve InjuryArmsEpineural suture, Non-operative treatment
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carin CarlssonDepartment of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden. carin.carlsson@regionstockholm.se.ORCID http://orcid.org/0000-0002-2848-3468
Johanna von KieseritzkyDepartment of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-4948-4512
Marianne ArnerDepartment of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-6744-9465
Cecilia Mellstrand NavarroDepartment of Clinical Science and Education, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3312-9375

Funding

Regional Agreement on Medical Training and Clinical Research (ALF) between the Stockholm County Council and Karolinska Institute FoUI-960047Region Stockholm FoUI-955404, FoUI-981655
6 · The paper itself

Abstract

backgroundInjuries to digital nerves in the hand are very common and result in sensory disturbances, which can have a major negative impact on hand function. The gold standard of treatment is end-to-end nerve repair with sutures, at the latest within 2 weeks from injury. Despite operative treatment of digital nerve injuries, the clinical results are often poor. Recent literature questions the evidence supporting surgical repair of digital nerve injuries in adults.

methodsIn this randomized controlled trial, we will allocate patients with injury to a single digital nerve to either surgical nerve repair and cast, or immobilization only. The primary outcome is the return of sensation, measured as static two-point discrimination, at 12 months after injury. Secondary outcomes include complications, the Semmes-Weinstein monofilament test, the Mini Sollerman hand function test, and patient-reported outcome measures. DISCUSSION: The lack of high-quality studies comparing surgical repair of digital nerve injuries to simple immobilization of the finger motivates the conduct of this randomized study.

trial registrationClinicalTrials.gov. TRN: NCT05536609. Registered on 08/23/2022.

Indexed as

Finger InjuriesFingersNeurosurgical ProceduresPeripheral Nerve InjuriesSuture TechniquesAdultFemaleHumansRandomized Controlled Trials as TopicRecovery of FunctionTime FactorsTreatment OutcomeDigital nerveDigital nerve injuryDigital nerve neurorraphyDigital nerve repairDigital nerve suture

Identifiers

PMID42642770
PMCPMC13508327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.