Evidence map›Paper›PMID 42642688›Full record

ArticleAIDS and behavior2026

Trends in Buprenorphine Prescribing Among Adults with Opioid Use Disorder and Coexisting HIV or Viral Hepatitis, 2015-2025.

Margaret G Miller, Ashley Hailer, Philip R Wang, Ann K Avery, Corrilynn O Hileman, David C Kaelber, Akhil Anand

Abstract read
PubMed Publisher
In one paragraph

Article in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Margaret G Miller *Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID http://orcid.org/0000-0003-1620-9303
Ashley Hailer *Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Philip R WangDepartment of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Ann K AveryCase Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID http://orcid.org/0000-0002-8106-9581
Corrilynn O HilemanCase Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID http://orcid.org/0000-0001-9849-0914
David C KaelberThe Center for Clinical Informatics Research and Education, MetroHealth System, and the Departments of Internal Medicine, Pediatrics, and Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID http://orcid.org/0000-0001-7855-9515
Akhil AnandDepartment of Psychiatry and Psychology, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA. ananda3@ccf.org.ORCID http://orcid.org/0000-0003-4132-2690

Funding

Research Support Core D: Clinical and Behavioral ServicesP30DA054557 · NIDA · CASE WESTERN RESERVE UNIVERSITY · PI LEVINE, ALAN DAVID · 2021 to 2025
$16.2M
Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University UM1TR004528NIDA NIH HHS P30 DA054557School of Medicine, Case Western Reserve University P30DA054557-01
6 · The paper itself

Abstract

We examined buprenorphine prescribing among adults in the United States with opioid use disorder or other opioid-related diagnoses and coexisting HIV, hepatitis B, or hepatitis C from 2015 to 2025. Using the TriNetX USA Minimal Date Shift Network, we constructed annual cohorts and assessed encounter-day buprenorphine prescribing, with and without chronic pain diagnoses. Prescribing rose from 6% in 2015 to 17% in 2020, then plateaued at 16-19% through 2025, with marked attenuation after 2020. Despite expanded prescriber eligibility, most were not prescribed buprenorphine at clinical contact, suggesting regulatory reform alone is insufficient and that integrated, systemic approaches are needed.

Indexed as

BuprenorphineHIVOpioid-related disordersViral hepatitis

Identifiers

PMID42642688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.