Evidence map›Paper›PMID 42642398›Full record

ArticleNature communications2026

Anchoring mechanism-inspired discovery of a bacterial P450 gene conferring resistance to auxin herbicides.

Yuanyuan Jiang, Junjie Zhang, Zhong Li, Lingyan Wang, Yuyu Guo, Yuxuan Li, Xisong Feng, Wen Gao, Yong Li, Zijia Li and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Yuanyuan Jiang *State Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Junjie Zhang *Qingdao KingAgroot CropScience Co., Ltd., Qingdao, China.
Zhong LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.ORCID http://orcid.org/0009-0003-1109-9448
Lingyan WangThe Key Laboratory of Plant Development and Environmental Adaptation Biology, School of Life Sciences, Shandong University, Qingdao, China.
Yuyu GuoState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Yuxuan LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Xisong FengState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Wen GaoQingdao KingAgroot CropScience Co., Ltd., Qingdao, China.
Yong LiQingdao KingAgroot CropScience Co., Ltd., Qingdao, China.
Zijia LiSchool of Food Science and Pharmaceutical Engineering, State Key Laboratory of Microbial Technology, Nanjing Normal University, Nanjing, China.
Jieke DuState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.ORCID http://orcid.org/0009-0004-8057-4641
Guoqiang ZhangState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.ORCID http://orcid.org/0009-0003-7008-0579
Piqian GongState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.
Wenhan FangCollege of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.
Xiang GaoState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China.ORCID http://orcid.org/0000-0001-6397-5639
Mingyi BaiThe Key Laboratory of Plant Development and Environmental Adaptation Biology, School of Life Sciences, Shandong University, Qingdao, China.ORCID http://orcid.org/0000-0001-5992-7511
Frank HollmannDepartment of Biotechnology, Delft University of Technology, Delft, The Netherlands.ORCID http://orcid.org/0000-0003-4821-756X
Mei ZhangGuangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, China.
He HuangSchool of Food Science and Pharmaceutical Engineering, State Key Laboratory of Microbial Technology, Nanjing Normal University, Nanjing, China.ORCID http://orcid.org/0000-0002-6833-9815
Binju WangCollege of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China.ORCID http://orcid.org/0000-0002-3353-9411
Sudong MoQingdao KingAgroot CropScience Co., Ltd., Qingdao, China. mosudong-qy@kingagroot.com.
Huarong LiQingdao KingAgroot CropScience Co., Ltd., Qingdao, China.
Wei PengState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China. weipeng@sdu.edu.cn.ORCID http://orcid.org/0000-0002-4085-5842
Shengying LiState Key Laboratory of Microbial Technology, Shandong University, Qingdao, China. lishengying@sdu.edu.cn.ORCID http://orcid.org/0000-0002-5244-870X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22121001National Natural Science Foundation of China (National Science Foundation of China) 22403094 and 22577066National Natural Science Foundation of China (National Science Foundation of China) 32025001National Natural Science Foundation of China (National Science Foundation of China) 32200017National Natural Science Foundation of China (National Science Foundation of China) 32300021Natural Science Foundation of Shandong Province (Shandong Provincial Natural Science Foundation) ZR2022QC070Natural Science Foundation of Shandong Province (Shandong Provincial Natural Science Foundation) ZR2023QC021Natural Science Foundation of Shandong Province (Shandong Provincial Natural Science Foundation) ZR2025QB36
6 · The paper itself

Abstract

Herbicides in combination with genetically modified herbicide-resistant crops have revolutionized modern weed management, increased crop yields, and facilitated farming practices. However, rapid evolution of herbicide-resistant weeds necessitates new resistance traits to sustain control efficacy. Here, we introduce a terminal carboxyl anchoring mechanism-inspired approach for precise discovery of P450 herbicide resistance genes, by which a number of bacterial P450 peroxygenases are predicted and confirmed to degrade auxin herbicides. Upon enzyme engineering, the optimal mutant P450

Indexed as

Bacterial ProteinsCytochrome P-450 Enzyme SystemHerbicide ResistanceHerbicidesIndoleacetic AcidsOryzaPlants, Genetically ModifiedPlant WeedsBacterial ProteinsCytochrome P-450 Enzyme SystemHerbicidesIndoleacetic Acids

Identifiers

PMID42642398
PMCPMC13507219

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.