Evidence map›Paper›PMID 42642088›Full record

ArticleInternational wound journal2026

Staged Management of Extensive Suprapubic Wound Necrosis After Hysterectomy Using Negative Pressure Wound Therapy and Delayed Skin Grafting.

Stefano Restaino, Edoardo Farnè, Martina Arcieri, Marta Bortolozzo, Anna Momic, Tina Moni Bidin, Beatrice Nonino, Irene Silvestri, Glenda Caputo, Marco D'Asta and 4 more

Abstract readCase Reports
In one paragraph

Article in International wound journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Stefano RestainoClinic of Obstetrics and Gynecology, "Santa Maria Della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Edoardo FarnèDepartment of Medicine (DMED), University of Udine, Udine, Italy.ORCID https://orcid.org/0009-0008-4351-4366
Martina ArcieriClinic of Obstetrics and Gynecology, "Santa Maria Della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Marta BortolozzoDepartment of Medicine (DMED), University of Udine, Udine, Italy.
Anna MomicDepartment of Medicine (DMED), University of Udine, Udine, Italy.
Tina Moni BidinDepartment of Medicine (DMED), University of Udine, Udine, Italy.
Beatrice NoninoDepartment of Medicine (DMED), University of Udine, Udine, Italy.
Irene SilvestriDepartment of Medicine (DMED), University of Udine, Udine, Italy.
Glenda CaputoPlastic and Reconstructive Surgery Department, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Marco D'AstaDepartment of Obstetrics and Gynecology, ARNAS Garibaldi Hospital, Catania, Italy.
Marco PetrilloDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.
Guglielmo StabileDepartment of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, Foggia, Italy.
Lorenza DriulClinic of Obstetrics and Gynecology, "Santa Maria Della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Giuseppe VizzielliClinic of Obstetrics and Gynecology, "Santa Maria Della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative wound complications are a major clinical challenge, especially in patients with comorbidities such as overweight and diabetes mellitus. Extensive abdominal wall necrosis after gynaecologic surgery is uncommon but may lead to prolonged healing, increased morbidity and the need for complex reconstructive procedures. Negative pressure wound therapy (NPWT) is an effective option for complex surgical wounds, promoting granulation tissue, improving perfusion and reducing bacterial burden. This report describes the case of a 58-year-old woman with overweight status and Type 2 diabetes mellitus who developed extensive suprapubic wound dehiscence with associated tissue necrosis following hysterectomy and bilateral salpingo-oophorectomy performed for a giant uterine leiomyoma. Following surgical debridement, NPWT was started and maintained with scheduled dressing changes. Progressive improvement was observed, with wound size decreasing from about 20 to 10 cm in 30 days and robust granulation tissue formation. Once the wound bed was optimised, definitive closure was achieved with an autologous skin graft. This case supports the role of NPWT as a bridge therapy in managing complex postoperative gynaecologic wounds in high-risk patients. A multidisciplinary approach involving gynaecologists, plastic surgeons and wound care specialists was essential for a favourable outcome. NPWT should be considered a valuable option for selected gynaecologic patients with extensive wound complications.

Indexed as

HysterectomyNecrosisNegative-Pressure Wound TherapySkin TransplantationSurgical Wound DehiscenceFemaleHumansLeiomyomaMiddle AgedTreatment OutcomeWound Healingcomplex woundsgynaecologic surgerymultidisciplinary approachnegative pressure wound therapysurgical wound dehiscence

Identifiers

PMID42642088
PMCPMC13506251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.