Evidence map›Paper›PMID 42640815›Full record

ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)2026

RECOVER Guidelines: First Aid. Evidence, Treatment Recommendations, Knowledge Gap Analysis, and Clinical Guidelines for Acute Allergy and Anaphylaxis in Dogs and Cats.

Jamie M Burkitt-Creedon, Deborah C Mandell, Vincent J Thawley, Daniel J Fletcher, Manuel Boller, Jonathan Ball, Corrin J Boyd, Fiona J L Brown, Melissa Evans, Erik Fausak and 7 more

Abstract read
In one paragraph

Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. RECOVER Guidelines: First Aid in Dogs and Cats. Evidence and Knowledge Gap Analysis With Treatment Recommendations.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2026
    Article
  2. RECOVER Guidelines: First Aid for Dogs and Cats. Clinical Guidelines.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jamie M Burkitt-CreedonDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.
Deborah C MandellDepartment of Clinical Sciences & Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Vincent J ThawleyDepartment of Clinical Sciences & Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Daniel J FletcherDepartment of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
Manuel BollerVCA Canada Central Victoria Veterinary Hospital, Victoria, British Columbia, Canada.
Jonathan BallNewtown Veterinary Specialists, Newtown, Connecticut, USA.
Corrin J BoydSchool of Veterinary Medicine, Murdoch University, Murdoch, Western Australia, Australia.
Fiona J L BrownLibrary & University Collections, The University of Edinburgh, Edinburgh, UK.
Melissa EvansMelissa E VTS(ECC) Consulting, LLC, Brooklyn, New York, USA.
Erik FausakUniversity Library, University of California, Davis, Davis, California, USA.
Thomas HackneySchool of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
Jiwoong HerNorth Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
Heather K MoberlyUniversity Libraries, The Pennsylvania State University, University Park, Pennsylvania, USA.
Lee E PalmerNational Association of Veterinary EMS (NAVEMS), Dover, Delaware, USA.
Laura M ReyDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Amanda WitsilCritical Relief LLC, Denver, Colorado, USA.
Ivayla YozovaSchool of Veterinary Science, Tāwharau Ora, Massey University, Palmerston North, New Zealand.

Funding

Boehringer Ingelheim Animal HealthZoetis Animal Health
6 · The paper itself

Abstract

objectiveTo systematically evaluate relevant evidence, devise and present treatment recommendations, and identify and present critical knowledge gaps regarding treatment of uncomplicated allergic reaction and anaphylaxis in dogs and cats.

designStandardized, systematic evaluation of literature pertinent to uncomplicated allergic reaction and anaphylaxis following Grading of Recommendations, Assessment, Development, and Evaluation methodology, modified for two clinical questions. Identified literature regarding prioritized questions in the Population-Intervention-Comparator-Outcome (PICO) format was reviewed independently by Evidence Evaluators, and findings were reconciled by Domain Chairs and Reassessment Campaign on Veterinary Resuscitation (RECOVER) Co-Chairs to arrive at treatment recommendations. This process used an evidence profile worksheet for each PICO question including an introduction, consensus on science, treatment recommendations, justification of recommendations, and knowledge gaps. Treatment recommendations underwent a 4-week comment period among international veterinary stakeholders prior to finalization. These 2026 RECOVER First Aid Guidelines: Acute Allergy and Anaphylaxis summarize treatment recommendations for dogs and cats.

settingTransdisciplinary, international collaboration in university, specialty, emergency, and general practice.

resultsSix PICO questions pertaining to uncomplicated allergic reaction and anaphylaxis were addressed in this subproject of the RECOVER First Aid Domain. These six PICO questions resulted in 12 treatment recommendations. All recommendations are supported by low or very low quality of evidence (7) or based on expert opinion (5). The RECOVER First Aid Acute Hypersensitivity Reaction Algorithm displays the flow of assessments and treatments for dogs and cats with uncomplicated allergic reaction and anaphylaxis.

conclusionsThese 2026 RECOVER First Aid Guidelines: Acute Allergy and Anaphylaxis present a concise and comprehensive framework for recognizing and treating acute hypersensitivity in dogs and cats. However, meaningful uncertainty remains regarding optimal diagnosis and treatment of these conditions in dogs and cats, and high-priority knowledge gaps are presented to guide collaborative clinical research in this area.

Indexed as

AnaphylaxisCat DiseasesDog DiseasesFirst AidHypersensitivityAnimalsCatsDogsPractice Guidelines as Topicanaphylaxisclinical guidelinesemergency careemergency medicineepinephrineevidence‐basedprehospitalurticaria

Identifiers

PMID42640815
PMCPMC13505870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.