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Association of routine laboratory parameters with chronic kidney disease-mineral and bone disorder in patients on maintenance hemodialysis: A retrospective study.
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6 authors.
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Abstract
ObjectiveTo investigate the associations between routine laboratory parameters and chronic kidney disease-mineral and bone disorder (CKD-MBD) in patients on maintenance hemodialysis (MHD).MethodsThis retrospective study collected data on demographic characteristics, medication interventions, and routine laboratory parameters from patients on MHD treated at the First Affiliated Hospital of Nanchang University in September 2025. Patients were classified into the CKD-MBD abnormal group if any of the following parameters exceeded the KDOQI guideline-recommended ranges: corrected serum calcium, serum phosphate, or parathyroid hormone (PTH). Patients with all three parameters within the recommended ranges were assigned to the CKD-MBD normal group. Differences in demographic characteristics, medication interventions, and laboratory parameters between groups were analyzed using SPSS version 25. Binary logistic regression analysis was performed to identify factors associated with CKD-MBD.ResultsA total of 546 patients were included, of whom 167 were classified into the CKD-MBD normal group and 379 into the abnormal group, yielding a prevalence of CKD-MBD abnormalities of 69.41%. Multivariate logistic regression analysis showed that, compared with patients with a dialysis vintage >10 years, those with a dialysis vintage <5 years had a significantly lower risk of CKD-MBD biochemical abnormalities (OR = 0.329,
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