Evidence map›Paper›PMID 42640712›Full record

ArticleAmerican journal of men's health

Improving Testosterone Therapy Adherence and Quality of Life Monitoring in Men With Hypogonadism: A Quality Improvement Project Using Patient-Reported Outcome Measures.

Candice Abrams, Kathryn Evans Kreider, Eleanor L Stevenson, Julie A Thompson

Abstract read
In one paragraph

Article in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Candice AbramsDuke University School of Nursing, Durham, NC, USA.ORCID 0009-0005-6244-6790
Kathryn Evans KreiderDuke University School of Nursing, Durham, NC, USA.
Eleanor L StevensonDuke University School of Nursing, Durham, NC, USA.ORCID 0000-0002-9937-8710
Julie A ThompsonDuke University School of Nursing, Durham, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testosterone deficiency syndrome in men is common and associated with substantial symptom burden and reduced quality of life. Although testosterone replacement therapy (TRT) can improve patient-reported outcomes, real-world benefit depends on consistent adherence and structured follow-up. In outpatient settings, adherence and symptoms are rarely assessed using validated patient-reported outcome measures (PROMs), limiting treatment monitoring. This project implemented a structured PROM workflow including the Morisky Medication Adherence Scale (MMAS-8), Aging Males' Symptoms (AMS) scale, and Short Form-8 Health Survey (SF-8™) to improve testosterone therapy adherence, symptom and quality of life monitoring in an outpatient men's health clinic. A quality improvement initiative was conducted among adult men receiving TRT. Participants completed validated PROMs at baseline, 6 weeks, and 12 weeks. Primary outcomes included adherence (MMAS-8) and PROM completion; secondary outcomes included follow-up attendance, quality of life (SF-8 PCS/MCS), symptom severity (AMS total/domains), and objective measures (testosterone and BMI). Fifty-four participants enrolled, and 50 completed 12-week follow-up (92.6% retention). MMAS-8 scores improved from baseline (

Indexed as

Hormone Replacement TherapyHypogonadismMedication AdherencePatient Reported Outcome MeasuresQuality ImprovementQuality of LifeTestosteroneAdultAgedHumansMaleMiddle AgedTestosteronehealth related quality of lifehypogonadismmedication adherencepatient-reported outcomestestosterone replacement therapy

Identifiers

PMID42640712
PMCPMC13519181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.