ArticleRheumatology (Oxford, England)2026
Self-efficacy in idiopathic inflammatory myopathies: associated factors, profiles and patient-reported outcomes.
Article in Rheumatology (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesSelf-efficacy (SE) is central to chronic disease self-management but remains poorly characterized in idiopathic inflammatory myopathies (IIMs). We aimed to identify factors associated with SE, characterize SE profiles and examine associations with patient-reported outcomes (PROs) in IIMs.
methodsCross-sectional data from 5802 participants across IIMs, other rheumatic diseases (RMDs) and non-rheumatic autoimmune diseases (nRAIDs) were analysed. SE was measured using the Self-Efficacy for Managing Chronic Disease (SEMCD) scale. Hierarchical regression identified factors independently associated with SE, and k-means clustering defined SE health profiles. Associations with PROs were examined in a separate multivariable model.
resultsIIM patients had lower SE (median SEMCD 5.3) than those with RMDs (5.8) and nRAIDs (6.5), with confidence lowest for managing fatigue and physical discomfort. In the fully adjusted integrated model (R² = 0.222), mental health comorbidity (B = -0.898) and financial difficulty (B = -0.734) were most strongly associated with lower SE, while regular exercise (B = 0.770) and family support (B = 0.150) were associated with higher SE. The PRO model explained 48.3% of SE variance (R² = 0.483); resilience was the strongest positive association, while fatigue and pain were negatively associated. Four SE health profiles were identified, including a clinically distinctive resilient-despite-burden subgroup (24%) with high symptom burden but preserved SE and mental health. Higher SE was associated with better physical and mental health, greater resilience and life satisfaction, and lower fatigue, pain and loneliness (all P < 0.001).
conclusionSE in IIMs is associated with modifiable socioeconomic and psychological factors and with better health outcomes. Profile-based stratification may help identify vulnerable subgroups and guide targeted interventions.
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