ReviewClinical & experimental metastasis2026
Noninvasive molecular imaging signatures of histopathological growth patterns in colorectal cancer liver metastases.
Review in Clinical & experimental metastasis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Colorectal cancer liver metastases (CRLM) are characterized by distinct histopathological growth patterns (HGPs), desmoplastic (dHGP) also called encapsulated, replacement (rHGP) and pushing (pHGP) types, which have major prognostic and therapeutic implications. HGPs can only be determined histologically after surgical resection. This review explores molecular imaging as a potential in vivo approach to predict and characterize HGPs non-invasively. Based on the biological hallmarks of each pattern regarding glucose metabolism, angiogenesis, hypoxia, fibrotic stromal activation and immune contexture, we outline how specific PET tracers can capture these features. [
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