Evidence map›Paper›PMID 42640409›Full record

ArticleInfection2026

Pembrolizumab in people with HIV-associated progressive multifocal leukoencephalopathy: a retrospective case series.

Leyli Ghaeni, Hartmut Stocker, Daniela Drauz, Pascal Migaud

Abstract read
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In one paragraph

Article in Infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leyli GhaeniDepartment of Infectious Diseases, St. Joseph Hospital Berlin-Tempelhof, Wüsthoffstrasse 15, 12101, Berlin, Germany. leyli.ghaeni@joseph-kliniken.de.
Hartmut StockerDepartment of Infectious Diseases, St. Joseph Hospital Berlin-Tempelhof, Wüsthoffstrasse 15, 12101, Berlin, Germany.
Daniela DrauzDepartment of Infectious Diseases, St. Joseph Hospital Berlin-Tempelhof, Wüsthoffstrasse 15, 12101, Berlin, Germany.
Pascal MigaudDepartment of Infectious Diseases, St. Joseph Hospital Berlin-Tempelhof, Wüsthoffstrasse 15, 12101, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive multifocal leukoencephalopathy (PML) in people with HIV (PWH) carries high mortality, and no specific antiviral treatment is available. In this retrospective single-centre case series of six patients treated with pembrolizumab, four showed clinical improvement or stabilisation. Pembrolizumab might represent a salvage option in this population.

Indexed as

HIV/AIDSPembrolizumabPML

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.