Evidence map›Paper›PMID 42640335›Full record

ArticleMarine biotechnology (New York, N.Y.)2026

Dietary Myo-Inositol Improves Growth, Antioxidant and Immune Responses in Bisphenol S-Exposed Procambarus clarkii.

Changchang Pu, Yuanyi Liu, Junhui Wang, Bingke Wang, Aimin Wang, Chunnuan Zhang

Abstract read
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In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Changchang PuCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, Henan, China.
Yuanyi LiuCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, Henan, China.
Junhui WangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, Henan, China.
Bingke WangHenan Academy of Fishery Sciences, Zhengzhou, 450044, China.
Aimin WangCollege of Marine and Bioengineering, Yancheng Institute of Technology, Yancheng, Jiangsu, 224051, China.
Chunnuan ZhangCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang, Henan, China. zhangchunnuan12@163.com.

Funding

Henan Province Natural Science Foundation 252300421415
6 · The paper itself

Abstract

Bisphenol S (BPS) is an emerging environmental contaminant that can disrupt oxidative and immune homeostasis in aquatic organisms, whereas myo-inositol (MI) is a water-soluble nutrient involved in growth and cellular signaling. This study evaluated growth, hepatopancreatic biochemical indices, and stress-related gene transcription in crayfish fed 0 or 1000 mg/kg supplemental MI and chronically exposed to 0-10 µg/L BPS for 6 weeks. Compared with the control group, the BPS group had significantly lower weight gain rate (WGR), specific growth rate (SGR), molting frequency, antioxidant enzyme activities (SOD, CAT, and POD), and immune enzyme activities (ACP, AKP, PO, and LZM), together with higher MDA content (P < 0.05). Compared with the BPS group, the MI + BPS group had significantly higher WGR, SGR, molting frequency, SOD, POD, ACP, and PO activities (P < 0.05). The MI + BPS group also showed higher nrf2 and hmc mRNA levels and lower keap1, bip, ire1, casp3, cytc, jnk, il-6, tnf-α, and nf-κb mRNA levels than the BPS group (P < 0.05). WGR, SGR, molting frequency, and hmc mRNA abundance in the MI + BPS group did not differ significantly from the control group (P > 0.05), the remaining endpoints showed indicator-specific responses. These findings indicate that dietary MI supplementation was associated with improved growth and selected antioxidant and immune indices, as well as altered transcription of genes related to oxidative, endoplasmic-reticulum-stress, inflammatory, and apoptosis-associated responses under BPS exposure. Pathway activation, tissue injury, and apoptosis were not directly assessed.

Indexed as

AntioxidantsAstacoideaInositolPhenolsSulfonesAnimalsBisphenol S CompoundsDietary SupplementsHepatopancreasOxidative StressWater Pollutants, ChemicalAntioxidantsbisphenol SBisphenol S CompoundsInositolPhenolsSulfonesWater Pollutants, ChemicalAntioxidantBisphenol SImmune responseMyo-inositolProcambarus clarkii

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.