ArticleJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2026
Construction of a nomogram for anxiety and depression in patients with Sjögren's syndrome by combining tongue and pulse characteristics: a cross-sectional study based on a prospective cohort.
Article in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo develop and validate a predictive model for predicting psychological complications of Sjögren's syndrome (SS) in combination with tongue and pulse characteristics.
methodsThis cross-sectional study was based on a prospective cohort study including SS patients recruited from 30 major tertiary hospitals in China. Nomograms were developed based on the clinical characteristics, tongue and pulse manifestations, and laboratory tests of these patients, and univariate and multivariate logistic regression analyses were used to screen for various correlates of anxiety and depression, and the column charts were evaluated using the area under the curve (AUC), calibration curves, and decision curve analysis.
resultsA total of 444 patients were included, comprising 424 females (95.5%) and 20 males (4.5%), with a mean age of (46 ± 13) years. The prevalence of anxiety and depression was 45.5% (
conclusionsIntegrating Traditional Chinese Medicine diagnostics with conventional clinical assessments provides a robust predictive model for psychological comorbidities in SS. The innovative approach enhances personalized management, offering a pathway for targeted interventions to treat anxiety and depression effectively in affected patients.
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