ArticleBioinformatics advances2026
Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Motivation: Model selection is a ubiquitous challenge in statistics. For penalized models, model selection typically entails tuning hyperparameters to maximize a measure of fit or minimize out-of-sample prediction error. However, these criteria fail to reflect other desirable characteristics, such as model sparsity, interpretability, or smoothness. Results: We present the R package pared for Pareto-based model selection using multi-objective optimization. The package provides a generic interface, pared_optimize(), that allows users to define model-specific tuning parameters, objective functions, and objective directions. Built-in wrappers are also provided for the elastic net, fused lasso, fused graphical lasso, and group graphical lasso. Gaussian process-based multi-objective optimization is used to approximate the Pareto front, and interactive graphics allow users to inspect trade-offs among fit, sparsity, smoothness, structural similarity, and other user-defined criteria. Availability and implementation: The pared R package and vignettes are available at https://github.com/priyamdas2/pared. The archived release corresponding to this manuscript is available on Zenodo with DOI: 10.5281/zenodo.20533535.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.