Evidence map›Paper›PMID 42639341›Full record

ArticleFrontiers in insect science2026

Potential for gene silencing by piwi-interacting RNA in three lepidopterans.

Santosh Poudel, Kevin Quito, Mosharrof Mondal, Kiran Nawaz, William Benjamin Walker, Alex Sutton Flynt

Abstract read
In one paragraph

Article in Frontiers in insect science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Santosh PoudelDepartment of Biomedical Engineering, University of Mississippi, University, MS, United States.
Kevin QuitoCellular and Molecular Biology, University of Southern Mississippi, Hattiesburg, MS, United States.
Mosharrof MondalRNAissance AG LLC, St. Louis, MO, United States.
Kiran NawazRNAissance AG LLC, St. Louis, MO, United States.
William Benjamin WalkerTemperate Tree Fruit and Vegetable Research Unit, United States Department of Agriculture - Agricultural Research Service (USDA-ARS), Wapato, WA, United States.
Alex Sutton FlyntDepartment of Biomedical Engineering, University of Mississippi, University, MS, United States.

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
NIGMS NIH HHS P20 GM103476
6 · The paper itself

Abstract

RNA interference (RNAi) has emerged as a promising strategy for insect pest control, yet its application in lepidopterans is hindered by insensitivity to double-stranded RNA (dsRNA). Here, we investigate the piwi-interacting RNA (piRNA) pathway as an alternative, mechanistically distinct gene silencing system in

Indexed as

biopesticidesgene silencingG-quadruplexpiwi-interaction RNA (piRNA)RNA interference (RNAi)

Identifiers

PMID42639341
PMCPMC13501171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.