Evidence map›Paper›PMID 42639263›Full record

ReviewFrontiers in cardiovascular medicine2026

Neurodevelopmental outcomes for pediatric ventricular assist device and heart transplant patients in the modern Era.

Shannon Oliver, Holger Buchholz, Darren H Freed, De Villiers Jonker, Ari R Joffe, Simon Urschel, Tara Pidborochynski, Joseph Atallah, Charlene M T Robertson, Jessica Zvonkovic and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shannon OliverDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Holger BuchholzDepartment of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Darren H FreedDepartment of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
De Villiers JonkerDepartment of Cardiac Surgery, University of Alberta, Edmonton, Alberta, Canada.
Ari R JoffeDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Simon UrschelDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Tara PidborochynskiDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Joseph AtallahDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Charlene M T RobertsonDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
Jessica ZvonkovicDepartment of Pediatrics, Glenrose Rehabilitation Hospital, Complex Pediatric Therapies Follow-up Program, Edmonton, Alberta, Canada.
Jennifer ConwayDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of patients who undergo pediatric ventricular assist device implantation or heart transplant are expected to survive to adulthood. However, there is limited research into what their neurodevelopmental and neurocognitive trajectories will be. This narrative mini review summarizes the literature available, demonstrating the significant burden of neurodevelopmental and neurocognitive difficulties in survivors, and highlights the importance of improving anticoagulation and developmental care in this population aiming for patients to reach their full potential. There is ongoing need for further research, and collaboratives such as the Advanced Cardiac Therapies Improving Outcomes Network can play an integral role in facilitating our understanding of the risk factors and long-term outcomes in this complex and high-risk patient population.

Indexed as

heart transplantoutcomespediatricreviewventricular assist device

Identifiers

PMID42639263
PMCPMC13501128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.