Evidence map›Paper›PMID 42639229›Full record

ArticleInternational journal of ophthalmology2026

Relationship between retinal nerve fibre thickness, suprasellar extension and post-operative visual outcome in pituitary macroadenoma.

Teck Chee Cheng, Mae-Lynn Catherine Bastion, Norshamsiah Md Din, Jegan Thanabalan, Kah Lay Oh, Seng Fai Tang, Diana Lim, Amalina Saiful Anwar, Safinaz Mohd Khialdin

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Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Teck Chee ChengDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.
Mae-Lynn Catherine BastionDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.
Norshamsiah Md DinDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.
Jegan ThanabalanHospital Canselor Tuanku Muhriz, Jalan Yaacob Latiff, Bandar Tun Razak, Cheras 56000, Kuala Lumpur, Malaysia.
Kah Lay OhDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.
Seng Fai TangDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.
Diana LimDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.
Amalina Saiful AnwarDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.
Safinaz Mohd KhialdinDepartment of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan, Malaysia, Cheras 56000, Kuala Lumpur, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the relationship between retinal nerve fibre layer (RNFL) thickness, suprasellar extension (SSE), tumour volume (TV) and visual outcome after pituitary adenoma surgery.

methodsA prospective observational study was conducted in a tertiary teaching hospital which included patients with pituitary macroadenoma who required surgical resection between December 2015 to February 2020. Agreeable subjects underwent complete ocular examination, Humphrey visual field (HVF) and RNFL measurement using spectral domain optical coherence tomography preoperatively and 3-month postoperatively. Post-operative visual outcome was evaluated using both best-corrected visual acuity (BCVA, logMAR) and HVF mean deviation (MD). TV was estimated by multiplying the transverse, anteroposterior, and craniocaudal maximum diameter; and SSE by measuring tumour extension beyond the supraclinoid internal carotid artery from magnetic resonance imaging.

resultsThirty-eight patients (18 males) were recruited. The mean age was 47.6±14.8y. The median and interquartile range (IQR) was 10.78 (6.45-16.94) cm

conclusionSSE shows stronger association with RNFL thinning than TV, and thicker pre-operative RNFL predicted better post-operative visual outcomes.

Indexed as

optical coherence tomographypituitary macroadenomaretinal nerve fibre layersuprasellar extensionvisual outcome

Identifiers

PMID42639229
PMCPMC13501025

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