Evidence map›Paper›PMID 42639169›Full record

ReviewThe MAK collection for occupational health and safety2026

1,3-Dichlorobenzene - Evaluation of a biological guidance value (BLW): Assessment Values in Biological Material - Translation of the German version from 2026.

Andrea Kaifie, Wobbeke Weistenhöfer, Thomas Kraus, Hans Drexler, Andrea Hartwig, MAK Commission

Abstract readReview
In one paragraph

Review in The MAK collection for occupational health and safety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea KaifieFriedrich-Alexander-Universität Erlangen-Nürnberg, Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine Henkestraße 9-11 91054 Erlangen Germany.
Wobbeke WeistenhöferFriedrich-Alexander-Universität Erlangen-Nürnberg, Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine Henkestraße 9-11 91054 Erlangen Germany.
Thomas KrausInstitute for Occupational, Social and Environmental Medicine, Uniklinik RWTH Pauwelsstraße 30 52074 Aachen Germany.
Hans DrexlerFriedrich-Alexander-Universität Erlangen-Nürnberg, Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine Henkestraße 9-11 91054 Erlangen Germany.
Andrea HartwigInstitute of Applied Biosciences, Department of Food Chemistry and Toxicology, Karlsruhe Institute of Technology (KIT) Adenauerring 20a, Building 50.41 76131 Karlsruhe Germany.
MAK Commission

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2025, the German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated a biological guidance value (BLW) for 1,3‑dichlorobenzene [541-73-1]. Relevant publications were identified from a literature search. For the derivation of the BLW, an experimental study was available that demonstrated a good correlation between the concentration of 1,3-dichlorobenzene in the air and 1,3-dichlorobenzene in blood as well as the urinary metabolites 3,5‑dichlorocatechol, 2,4‑dichlorophenol and 3,5-dichlorophenol. The data of the experimental study conducted with resting volunteers for 6-hours were extrapolated to account for an exposure of 8 hours and an increased respiratory volume at the work place. At the level of the MAK value of 2 ml/m

Indexed as

1,3-dichlorobenzene3,5-dichlorocatecholbiological guidance valueBLW

Identifiers

PMID42639169
PMCPMC13502088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.