Evidence map›Paper›PMID 42639060›Full record

ArticleJournal of oral microbiology2026

Probiotic intervention modulates volatile sulfur compound-associated pathways and oral microbiome balance in ligature-induced periodontitis rats.

Md Ariful Haque, Hye Kim, Jin Seock Moon, Seong Rok Sim, Md Abdur Razzak, Sehyeon Song, Jong Ik Jeon, Myeong Soo Park, Seockmo Ku

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Md Ariful HaqueDepartment of Food Science and Technology, Texas A&M University, College Station, TX, USA.
Hye KimDepartment of Food Science and Technology, Texas A&M University, College Station, TX, USA.
Jin Seock MoonResearch Center, BIFIDO Co., Ltd, Hongcheon, South Korea.
Seong Rok SimResearch Center, BIFIDO Co., Ltd, Hongcheon, South Korea.
Md Abdur RazzakDepartment of Food Science and Technology, Texas A&M University, College Station, TX, USA.
Sehyeon SongDepartment of Food Science and Technology, Texas A&M University, College Station, TX, USA.
Jong Ik JeonResearch Center, BIFIDO Co., Ltd, Hongcheon, South Korea.
Myeong Soo ParkResearch Center, BIFIDO Co., Ltd, Hongcheon, South Korea.
Seockmo KuDepartment of Food Science and Technology, Texas A&M University, College Station, TX, USA.ORCID https://orcid.org/0000-0003-2661-5073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Halitosis is driven by volatile sulfur compounds (VSCs) produced by anaerobic oral bacteria and commonly worsens with periodontitis. We investigated whether the probiotic complex Complex OK suppresses VSC pathways, modulates oral dysbiosis, and reduces inflammation. Materials and methods: Complex OK was evaluated Results: Complex OK reduced Conclusions: Complex OK may represent a noninvasive probiotic strategy for modulating halitosis-associated molecular pathways, supporting oral microbiome balance, and reducing periodontal inflammation, with potential as an adjunctive therapy for periodontal care pending further clinical validation.

Indexed as

Halitosisligature-inducedoral dysbiosisperiodontitisprobiotics

Identifiers

PMID42639060
PMCPMC13501734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.