Surface engineered nitrogen doped carbon quantum dots for mechanistic understanding and advanced biosensing of antibiotic contaminants: a review.

Shakeela Bibi, Chenyang Li, Salina Y Saddick, Lulu Xu, Yufeng Wang, Hao Zhang, Muhammad Awais, Iskander Tlili, Junfeng Wu, Jiandong Hu

Abstract readReview

PubMed Full text at PMC Publisher

In one paragraph

Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Shakeela BibiHenan International Joint Laboratory of Laser Technology in Agriculture Sciences, College of Mechanical and Electrical Engineering, Henan Agricultural University Zhengzhou 450002 Henan China jfwu@henau.edu.cn jdhu@henau.edu.cn.

Chenyang LiHenan International Joint Laboratory of Laser Technology in Agriculture Sciences, College of Mechanical and Electrical Engineering, Henan Agricultural University Zhengzhou 450002 Henan China jfwu@henau.edu.cn jdhu@henau.edu.cn.

Salina Y SaddickDepartment of Biological Sciences, Faculty of Science, King Abdulaziz University Jeddah Saudi Arabia.

Lulu XuHenan International Joint Laboratory of Laser Technology in Agriculture Sciences, College of Mechanical and Electrical Engineering, Henan Agricultural University Zhengzhou 450002 Henan China jfwu@henau.edu.cn jdhu@henau.edu.cn.

Yufeng WangUnited Graduate School of Chinese Modern Agriculture (UGSCMA) Zhengzhou 450002 Henan China.

Hao ZhangHenan International Joint Laboratory of Laser Technology in Agriculture Sciences, College of Mechanical and Electrical Engineering, Henan Agricultural University Zhengzhou 450002 Henan China jfwu@henau.edu.cn jdhu@henau.edu.cn.

Muhammad AwaisHenan International Joint Laboratory of Laser Technology in Agriculture Sciences, College of Mechanical and Electrical Engineering, Henan Agricultural University Zhengzhou 450002 Henan China jfwu@henau.edu.cn jdhu@henau.edu.cn.

Iskander TliliDepartment of Mechanical Engineering, Faculty of Engineering, Islamic University of Madinah Madinah 42351 Saudi Arabia itlili@iu.edu.sa.ORCID https://orcid.org/0000-0002-3007-5930

Junfeng WuHenan International Joint Laboratory of Laser Technology in Agriculture Sciences, College of Mechanical and Electrical Engineering, Henan Agricultural University Zhengzhou 450002 Henan China jfwu@henau.edu.cn jdhu@henau.edu.cn.

Jiandong HuHenan International Joint Laboratory of Laser Technology in Agriculture Sciences, College of Mechanical and Electrical Engineering, Henan Agricultural University Zhengzhou 450002 Henan China jfwu@henau.edu.cn jdhu@henau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrogen-doped carbon quantum dots (N-CQDs) have emerged as a versatile platform for antibiotic biosensing, yet the field has been hindered by empirical optimization without mechanistic understanding. This review establishes quantitative structure-property-performance relationships that enable rational sensor design. We demonstrate that surface chemistry tuning, specifically the density of carboxylic acid groups and the ratio of carboxylic acid to amino functionalities, governs tetracycline binding affinity, while nitrogen doping levels and their distribution among pyridinic, pyrrolic, and graphitic configurations determine the dominant charge transfer pathways. Pyridinic N is identified as an important contributor to photoinduced electron transfer, showing a reported correlation with Stern-Volmer constants (

Identifiers

PMID42639032

DOI10.1039/d6ra05941d

PMCPMC13501471

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