ArticleFrontiers in bioengineering and biotechnology2026
Modulating silver diamine fluoride chemical derivatives by solid-binding peptides.
Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Embrace Disorder as a Function: Bio-Informed Biomaterials Design Advanced by Intrinsically Disordered Proteins.Biomimetics (Basel, Switzerland) · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
Peptide modulators offer a means to transition from passive dental treatment to actively designing the biological interface with specific responses for efficacy and minimal off-target effects. The oral cavity is exposed to one of the most hostile and dynamic environments in the human body. Targeted delivery of peptide modulators may direct the desired biological outcomes at the interface of dental bioceramic tissues. While noninvasive silver diamine fluoride (SDF) has revolutionized cavity management in early childhood caries, its universal use is limited by its drawbacks including permanent black stain on treated tissues. To mitigate these drawbacks, we investigated the effects of a silver diamine fluoride modulating peptide (SDF-ModP) on silver compound formation and staining outcomes in SDF-treated dentin. Slabs of human dentin tissue were treated with SDF alone or SDF followed by SDF-ModP. Raman micro-spectroscopy and X-ray photoelectron spectroscopy (XPS) were used to identify the silver compounds. The color change was monitored over time using the CIELAB color space. Raman analysis identified silver chloride (AgCl), silver (I) oxide (Ag
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