ArticleJournal of analytical methods in chemistry2026
Development and Validation of an UPLC-MS/MS Method for Remodelin Quantification in Mouse Plasma and Tissues: Application to Biodistribution and Ultrastructural Assessment.
Article in Journal of analytical methods in chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Development and Validation of an UPLC-MS/MS Method for Remodelin Quantification in Mouse Plasma and Tissues: Application to Biodistribution and Ultrastructural Assessment.Journal of analytical methods in chemistry · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Remodelin, a selective N-acetyltransferase 10 (NAT10) inhibitor, has emerged as a promising therapeutic candidate for degenerative diseases with nuclear abnormalities and acetylation dysregulation. However, its pharmacological development has been hindered by the lack of a sufficiently sensitive bioanalytical method. To address this limitation, a simple, sensitive, and reliable ultra-performance liquid chromatography coupled to tandem mass spectrometry (UPLC-MS/MS) method was established and fully validated. This method achieved accurate quantification of remodelin at low pg/mL levels, representing a significant improvement in sensitivity and excellent linearity (
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Registered trials
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