Evidence map›Paper›PMID 42638862›Full record

ArticleInternational journal of ophthalmology2026

Safety and efficacy of micropulse transscleral laser therapy for glaucoma: a two-year follow-up.

Michele Lanza, Italo Fattore, Salvatore Ambrosio, Francesco Abbate, Rosa Boccia, Luigi Serra, Teresa Cangiano, Francesca Simonelli

Abstract read
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In one paragraph

Article in International journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michele LanzaMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.
Italo FattoreMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.
Salvatore AmbrosioMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.
Francesco AbbateMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.
Rosa BocciaMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.
Luigi SerraMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.
Teresa CangianoMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.
Francesca SimonelliMultidisciplinary Department of Medical, Surgical and Dental Specialities, University of Campania Luigi Vanvitelli, Napoli 80100, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the efficacy and safety of micropulse transscleral laser therapy (MP-TLT) in lowering intraocular pressure (IOP) in eyes with primary glaucoma at different stages.

methodsIn this retrospective longitudinal cohort study, data were collected from the charts of patients who undergo MP-TLT. Information regarding medication burden (including oral carbonic anhydrase inhibitor use), IOP, and visual acuity, were gathered prior to the procedure and at day 1, week 1 and at 1, 3, 6, 12, 18, and 24mo follow-up. Glaucoma severity staging was performed according to the Hodapp-Parrish-Anderson classification system based on visual field parameters assessed with standardized automated perimetry. Early glaucoma was defined as mean deviation (MD) better than -6 dB, moderate glaucoma as MD between -6 and -12 dB, and advanced glaucoma as MD worse than -12 dB.

resultsTotally 84 eyes of 53 patients (22 females), with a mean age of 67.14±11.39y affected by progressive primary open angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) were included. Before treatment, mean best corrected visual acuity was 0.26±0.36 logMAR, mean IOP was 22.32±6.64 mm Hg and patients took a mean of 2.96±0.75 topical IOP lowering molecules; moreover, 18 patients also required acetazolamide tablets. At 1mo follow-up, a significant (

conclusionThe results obtained suggest that MP-TLT may be an effective and safe option for managing patients with POAG and PACG at every stage of the disease.

Indexed as

intraocular pressuremicropulse transscleral laser therapyprimary angle-closure glaucomaprimary open angle glaucoma

Identifiers

PMID42638862
PMCPMC13501046

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.