ArticleFrontiers in tuberculosis2025
Risk factors associated with multidrug-resistant pulmonary tuberculosis in patients over 15 years old: a retrospective case-control study.
Article in Frontiers in tuberculosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Population-level and longitudinal MIC distributions for antimicrobials against drug-resistantFrontiers in cellular and infection microbiology · 2026Article
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4 authors.
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Abstract
Introduction: Multidrug-Resistant Pulmonary Tuberculosis (MDR-TB) represents a serious public health problem, hindering disease control and increasing morbidity and mortality. This study aimed to identify risk factors associated with MDR-TB in patients over 15 years old at the Sanatorium Hospital of Luanda during the period 2015-2016. Methods: A retrospective case-control study (1:1) was conducted with 500 participants, including 250 cases (MDR-TB) and 250 controls (drug-sensitive TB). Data were obtained from clinical records and analyzed using logistic regression in Epi-Info 7.2.1.0 software, considering a significance level of Results: MDR-TB was more prevalent in men (61.6%), in the age group 20-29 years (36.8%), and among employed individuals (73.2%). The associated risk factors were irregular medication adherence [odds ratio (OR) = 12.3; Conclusion: Irregular adherence to treatment and a history of previous TB were the main factors associated with MDR-TB, reinforcing the need for effective strategies to ensure treatment follow-up.
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