SynthesisFrontiers in medicine2026
Association between history of pulmonary tuberculosis and chronic obstructive pulmonary disease: a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Survivors of pulmonary tuberculosis (TB) frequently report chronic respiratory symptoms; however, the magnitude of the association with chronic obstructive pulmonary disease (COPD) and the reciprocal burden of COPD and TB in each population remain unclear. Hence, this review was conducted to determine the association between a history of pulmonary tuberculosis and chronic obstructive pulmonary disease. Methods: Following PRISMA 2020, we searched MEDLINE, Embase, Web of Science, and Scopus from inception to August 2025 for analytical observational studies comparing individuals with and without a history of pulmonary TB. Odds ratios (ORs) were pooled using random-effects inverse-variance models (DerSimonian-Laird). Heterogeneity ( Results: Forty studies met the inclusion criteria. Twenty-six studies ( Conclusion: A history of pulmonary TB was found to be a strong and consistent risk factor for COPD across different designs and regions, with a significant bidirectional burden. Integrating post-TB lung assessment (including spirometry), targeted COPD management, and risk-reduction strategies into TB programs is required. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261415397, PROSPERO registration number is CRD420261415397.
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