Evidence map›Paper›PMID 42638729›Full record

ArticleFrontiers in surgery2026

Emergency liver transplantation combined with multivisceral resection after severe abdominal trauma: a case report.

Marco Brolese, Matteo Pittacolo, Alessandro Vitale, Domenico Bassi, Alberto Friziero, Enrico Gringeri, Annalisa Dolcet, Francesco E D'Amico, Riccardo Boetto, Jacopo Lanari and 7 more

Abstract readCase Reports
In one paragraph

Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Marco Brolese *Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Matteo Pittacolo *1st General Surgery, Acute Care Surgery Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Alessandro VitaleHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Domenico BassiHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Alberto Friziero1st General Surgery, Acute Care Surgery Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Enrico GringeriHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Annalisa DolcetHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Francesco E D'AmicoHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Riccardo BoettoHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Jacopo LanariHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Alessandro FurlanettoHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Alessandra BertaccoHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Gianfranco Da Dalt1st General Surgery, Acute Care Surgery Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Renato Salvador1st General Surgery, Acute Care Surgery Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Alberto BroleseDepartment of General Surgery and Hepato-Pancreato-Biliary Surgery, Azienda Sanitaria Universitaria Integrata del Trentino (ASUIT), Trento, Italy.
Michele Valmasoni1st General Surgery, Acute Care Surgery Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.
Umberto CilloHepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, Department of Surgery, Oncology and Gastroenterology, University of Padova, Azienda Ospedale Università Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Liver transplantation (LT) after severe polytrauma is exceptionally rare. When damage-control surgery fails, multiorgan resection may be required as a life-saving procedure, with emergency LT representing the ultimate salvage option for patients with uncontrollable hepatic hemorrhage or irreversible liver failure. We report, to our knowledge, the first documented case of concomitant liver transplantation, splenectomy, nephrectomy, and total pancreatectomy following severe abdominal trauma. Case presentation: A 19-year-old male sustained severe blunt abdominal trauma following a motorcycle-truck collision. Imaging revealed an AAST grade V liver injury with major vascular and biliary disruption, complete avulsion of the right renal artery (AAST V), splenic injury (AAST III) and an AAST grade II duodenal hematoma. Despite damage-control surgery, followed by splenectomy and right nephrectomy, definitive hemorrhage control could not be fully achieved. Given the persistent hepatic bleeding and the expected progression to acute liver failure secondary to extensive hepatic disruption, the patient underwent emergent LT. Due to concerns for progression of the duodenal injury, a planned second-look operation was performed 48 h later, revealing marked enlargement of the hematoma with impending duodenal wall rupture, prompting the decision to proceed with total pancreatectomy. The postoperative course was uneventful, and the patient was discharged 18 days after transplantation. At 29-month follow-up, both graft function and clinical status are excellent. Conclusions: Emergency LT may represent a feasible and life-saving strategy in highly selected patients with devastating abdominal trauma. This case demonstrates that, despite the extreme surgical complexity, favorable long-term outcomes can be achieved, supporting the non-futility of transplantation in carefully selected trauma recipients.

Indexed as

case reportdamage control surgeryemergency surgeryliver injuryliver transplantationmultivisceral resectionpolytrauma

Identifiers

PMID42638729
PMCPMC13500773

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.