Evidence map›Paper›PMID 42638443›Full record

ArticleMedical physics2026

Modified Z-resolution protocol for digital breast tomosynthesis.

Priyash Singh, Nyasha G Maforo, Bruno Barufaldi, Andrew D A Maidment, Raymond J Acciavatti

Abstract read
In one paragraph

Article in Medical physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Priyash SinghDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Nyasha G MaforoDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Bruno BarufaldiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Andrew D A MaidmentDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Raymond J AcciavattiDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

High Performance, Quantitative Breast PET Scanner Integrated With TomosynthesisR01CA196528 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ANDREW DOUGLAS ARNOLD MAIDMENT, Suleman Surti · 2016 to 2026
$5.9M
Next-Generation Tomosynthesis Pilot StudyR37CA273959 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Raymond Joseph Acciavatti · 2022 to 2026
$1.8M
Institute for Translational Medicine and TherapeuticsNCI NIH HHS R01 CA196528NCI NIH HHS R37 CA273959NIH HHS R01CA196528NIH HHS R37CA273959
6 · The paper itself

Abstract

backgroundThe EUREF protocol measures the z-resolution of a digital breast tomosynthesis (DBT) system via a ball bearing's (BB) point-spread function (PSF) and is quantified as the full-width at half-maximum (FWHM) of the associated artifact spread function (ASF). PSF is largely governed by the apparent angle ( PURPOSE: The purpose of this work was to develop a z-resolution metric that more rigorously reflects the underlying local PSF's

methodsThe protocol was evaluated using analytically simulated and experimentally acquired DBT reconstructions of BBs displaced anteriorly and superiorly and compared against the EUREF protocol. The percent change in FWHM due to stochastic noise was used to quantify systematic noise susceptibility. The strength of the anti-correlation between FWHM and apparent angle α was used to assess each protocol's agreement with the PSF geometry.

resultsBy demonstrating a consistent linear anti-correlation between FWHM and α for both superior and anterior BB displacements, the Modified protocol faithfully captures the spatial variation in PSF. The Modified protocol also substantially reduces the noise-induced FWHM shift-by 98% in simulations and 84% in physical experiments-relative to the EUREF protocol.

conclusionsThe EUREF protocol exhibits systematic errors which can limit its reliability in characterizing the z-resolution. Our Modified protocol mitigates these shortcomings and restores concordance between measured z-resolution and the underlying local PSF geometry (

Indexed as

MammographyRadiographic Image EnhancementArtifactsHumansImage Processing, Computer-Assistedartifact spread functiondigital breast tomosynthesispoint spread function

Identifiers

PMID42638443
PMCPMC13504301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.