Evidence map›Paper›PMID 42638164›Full record

ArticleLower urinary tract symptoms2026

Safety and Efficacy of Rezūm Water Vapor Energy Therapy for Benign Prostatic Hyperplasia With Continued Antithrombotic Therapy: A Comparative Study.

Naoki Fujisawa, Satoshi Washino, Yuka Yasuda, Shigetoshi Maiya, Tetsuo Shinozaki

Abstract readComparative Study
In one paragraph

Article in Lower urinary tract symptoms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Naoki FujisawaDepartment of Urology, IMS Fujimi General Hospital, Fujimi, Japan.ORCID https://orcid.org/0009-0006-3928-0486
Satoshi WashinoDepartment of Urology, Jichi Medical University Saitama Medical Center, Saitama, Japan.ORCID https://orcid.org/0000-0001-9464-6424
Yuka YasudaDepartment of Urology, IMS Fujimi General Hospital, Fujimi, Japan.
Shigetoshi MaiyaDepartment of Urology, IMS Fujimi General Hospital, Fujimi, Japan.
Tetsuo ShinozakiDepartment of Urology, IMS Fujimi General Hospital, Fujimi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEvidence regarding the safety of water vapor energy (WAVE) therapy in patients continuing antithrombotic (AT) agents remains limited. This study compared the safety and efficacy of WAVE therapy between patients receiving AT therapy and those not receiving such therapy.

methodsThis retrospective comparative study included 103 consecutive patients who underwent WAVE therapy at a single institution between February 2023 and October 2024. Patients were divided into an AT group (n = 36) and a non-AT group (n = 67). All AT agents continued throughout the perioperative period. Postoperative complications were graded according to the Clavien-Dindo classification. Changes in symptom scores and uroflowmetry parameters were evaluated at baseline and at 3 and 6 months after treatment in patients without a preoperative indwelling catheter.

resultsBaseline characteristics were generally similar between the two groups, although patients in the AT group were significantly older than those in the non-AT group. Early postoperative bleeding events were comparable (11.1% in the AT group vs. 4.5% in the non-AT group, p = 0.24), and no grade ≥ 3 complications occurred in either group. Late complications occurred only in the non-AT group (6.0%). In the overall cohort, the median IPSS total score decreased from 18.5 (interquartile range: 12.0-25.0) at baseline to 9.0 (3.0-12.8) and 6.0 (3.0-10.8) at 3 and 6 months, respectively. Post-void residual volume decreased from 111 (interquartile range: 52.8-180) mL at baseline to 55.5 (27.3-102) and 50.5 (24.5-92.3) mL. These improvements were comparable between groups.

conclusionsWAVE therapy appeared feasible in patients who continued AT therapy, with acceptable short-term safety and symptomatic improvement.

Indexed as

Fibrinolytic AgentsProstatic HyperplasiaSteamAgedHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeFibrinolytic AgentsSteamantithrombotic agentsbenign prostatic hyperplasiacomplicationsefficacyhematuriawater vapor thermal therapy

Identifiers

PMID42638164
PMCPMC13503971

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.