Evidence map›Paper›PMID 42638150›Full record

ArticleInfectious diseases of poverty2026

Contrasting patterns of trematode and host snail dispersal across clusters of tropical crater lakes.

Cyril Hammoud, Bert Van Bocxlaer, Julius Tumusiime, Dirk Verschuren, Christian Albrecht, Casim Umba Tolo, Tine Huyse

Abstract read
In one paragraph

Article in Infectious diseases of poverty, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cyril HammoudLimnology Unit, Department of Biology, Ghent University, 9000, Ghent, Belgium. cyril.hammoud@nioz.nl.ORCID https://orcid.org/0000-0001-5367-1404
Bert Van BocxlaerLimnology Unit, Department of Biology, Ghent University, 9000, Ghent, Belgium.
Julius TumusiimeDepartment of Biology, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Dirk VerschurenLimnology Unit, Department of Biology, Ghent University, 9000, Ghent, Belgium.
Christian AlbrechtDepartment of Biology, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Casim Umba ToloDepartment of Biology, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.
Tine HuyseDepartment of Biology, Royal Museum for Central Africa, 3080, Tervuren, Belgium.

Funding

Belgian Research Action through Interdisciplinary Networks BR/165/PI/TRAILFrench Ministère de l'Enseignement Supérieur et de la Recherche, the Hauts-de-France Region and the European Funds for Regional Economic Development CPER ECRINResearch Foundation-Flanders 11C5221NResearch Foundation-Flanders K204519N
6 · The paper itself

Abstract

backgroundComparing the genetic diversity and population structure of parasites and their hosts can improve understanding of their respective methods of dispersal, demographic histories, and factors driving genetic differentiation. In parasite taxa such as trematodes which have both intermediate and final hosts, comparative population-level analyses may also inform how each host influences gene flow among parasite populations. Here we aimed to assess how intermediate and final hosts influence trematode dispersal by examining the population genetic structure of the aquatic snail Bulinus tropicus and three trematodes that use it as intermediate host.

methodsWe used high-throughput amplicon sequencing to simultaneously genotype populations of B. tropicus in two clusters of crater lakes in western Uganda (823 snails, 15 lakes) and three infecting trematode taxa (Petasiger sp., Echinoparyphium sp. and Plagiorchioidea sp.). For each taxon, we quantified genetic diversity in three mitochondrial markers and used analyses of molecular variance to test whether populations were genetically differentiated.

resultsPopulations of B. tropicus were strongly genetically differentiated among individual crater lakes and lake clusters (Φ

conclusionsContrasting patterns of genetic diversity and population structure among three parasitic trematodes and their common intermediate snail host illustrate how multi-host life cycles mediate dispersal dynamics and generate distinct evolutionary outcomes in hydrographically fragmented aquatic habitats. These findings demonstrate how multi-host life cycles shape parasite connectivity and evolution, and show that comparative population genetics can provide valuable insights into the dispersal ecology of understudied parasite species.

Indexed as

Genetic VariationHost-Parasite InteractionsLakesSnailsTrematodaAnimalsGenotypeHaplotypesUgandaAlbertine Rift ValleyComparative population geneticsHaplotype networkHost-parasite phylogeographyNext-generation sequencing

Identifiers

PMID42638150
PMCPMC13501632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.