Left ventricular stroke volume index predicts outcomes in asymptomatic chronic severe primary mitral regurgitation.

Porntera Sethalao, Nithima Ratanasit, Decho Jakrapanichakul, Sasima Tongsai, Sirichai Jamnongprasatporn

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Article in Journal of cardiovascular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Porntera SethalaoDivision of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Nithima RatanasitDivision of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Decho JakrapanichakulDivision of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Sasima TongsaiResearch Department, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Sirichai JamnongprasatpornDivision of Cardiology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. hokhok66@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere primary mitral regurgitation (MR) linked to substantial morbidity and mortality. However, racial differences impact the left ventricular size, which subsequently influence specific echocardiographic parameters. In this context, the left ventricular stroke volume index (LVSVi) may serve as a valuable prognostic indicator. This study aims to examine the association between LVSVi and a composite endpoint of all-cause mortality or mitral valve (MV) surgery.

methodsWe conducted a retrospective study on asymptomatic chronic severe primary MR patients over a 5-year follow-up period.

resultsAmong 77 patients with asymptomatic severe primary MR (mean age, 56.9 years; 55 male patients, 71.4%), an increase of 1 mL/m

conclusionsIn patients with asymptomatic chronic severe primary MR, LVSVi was the significant echocardiographic parameter influencing the outcomes of MV surgery and mortality. This study supported the hypothesis generation that LVSVi may serve as a prognostic marker in this specific population.

Indexed as

Left ventricular stroke volume indexMitral regurgitationMitral valve interventionMitral valve surgery

Identifiers

PMID42638144

DOI10.1186/s44348-026-00088-3

PMCPMC13501855

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