Evidence map›Paper›PMID 42638086›Full record

Observational studyBMC ophthalmology2026

Incremental contribution of Corvis ST dynamic biomechanical parameters to interpretable machine learning prediction of clinician-selected refractive procedures: a retrospective observational study.

Yinhao Li, Gang Li, Chuanyun Xu, Jiahui Wang, Xin Wang, Yanli Peng

Abstract readObservational Study
In one paragraph

Observational study in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yinhao Li *School of Artificial Intelligence, Chongqing University of Technology, Chongqing, 400054, China.
Gang Li *School of Artificial Intelligence, Chongqing University of Technology, Chongqing, 400054, China.
Chuanyun XuSchool of Computer and Information Science, Chongqing Normal University, Chongqing, 401331, China.
Jiahui WangDepartment of Refractive Surgery, Chongqing Aier Eye Hospital, Chongqing, 400020, China.
Xin WangSchool of Artificial Intelligence, Chongqing University of Technology, Chongqing, 400054, China.
Yanli PengDepartment of Refractive Surgery, Bright Eye Hospital Group Co., Ltd., Chongqing, 400013, China. pengyl@purui.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate whether structured preoperative variables can reproduce clinician-selected refractive procedure patterns and to assess the incremental contribution of Corvis ST dynamic biomechanical parameters beyond conventional refractive, tomographic, pachymetric, and risk-related features.

methodsWe conducted a retrospective observational study of 395 patients (763 eyes) who underwent refractive surgery at Chongqing Aier Eye Hospital between October 2023 and November 2024. The outcome label was the procedure actually selected and performed by clinicians, including ICL, SMILE, LASIK, and SURFACE. Forty-eight structured preoperative features were analyzed, including demographic, refractive, visual, ocular-surface, tomographic, pachymetric, anterior-segment, Pentacam-derived deviation/risk, and Corvis ST-derived variables. Data were split at the patient level into a training cohort and an internal held-out test cohort. Multiple machine learning models were developed using patient-grouped cross-validation, and the final model was evaluated using accuracy, balanced accuracy, macro-F1 score, class-wise metrics, calibration analysis, patient-level clustered bootstrap resampling, and one-eye-per-patient sensitivity analysis. Structured feature-set ablation and SHAP analysis were performed to evaluate feature-domain contributions and model behavior.

resultsThe two-stage XGBoost-based model, which first separated ICL from corneal laser procedures and then classified laser procedures into SMILE, SURFACE, and LASIK, achieved the most favorable overall performance. Its estimated total validation accuracy was 83.36% ± 2.59%. On the internal held-out test cohort, the model achieved an end-to-end accuracy of 78.43%, balanced accuracy of 79.17%, macro-F1 score of 77.96%, and macro AUC of 93.77%. Ablation analysis showed that most predictive gain was derived from tomographic and pachymetric variables, whereas pure Corvis ST dynamic biomechanical parameters provided modest complementary information beyond the full non-pure-Corvis feature set. SHAP analysis indicated that refractive parameters were the dominant contributors, while tomographic, pachymetric, risk-related, and Corvis ST-derived variables contributed to procedure-specific model behavior.

conclusionsStructured preoperative variables can partially reproduce single-center clinician-selected refractive procedure patterns. Corvis ST-derived dynamic biomechanical parameters suggested modest complementary predictive information beyond conventional refractive, tomographic, pachymetric, and risk-related features. These findings support internally validated prediction of clinician-selected procedure patterns but do not establish optimal surgical recommendation or external generalizability.

Indexed as

CorneaMachine LearningMyopiaRefraction, OcularRefractive Surgical ProceduresAdultBiomechanical PhenomenaCorneal PachymetryCorneal TopographyFemaleHumansMaleMiddle AgedPredictive Learning ModelsRetrospective StudiesYoung AdultArtificial intelligenceCorneal biomechanicsMachine learningPrediction modelProcedure selectionRefractive surgery

Identifiers

PMID42638086
PMCPMC13501657

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.