Evidence map›Paper›PMID 42637951›Full record

ArticleSurgical endoscopy2026

Outcomes of laparoscopic reoperation for anastomotic leak-associated peritonitis following colorectal cancer surgery: a comparative study.

Katsuhiro Ogawa, Yuji Miyamoto, Ayane Kawata, Takahiko Akiyama, Kota Arima, Keisuke Kosumi, Kojiro Eto, Kazuto Hadara, Yukiharu Hiyoshi, Masaaki Iwatsuki

Abstract read
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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Katsuhiro OgawaDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan. katsuhiro.ogawa1201@gmail.com.ORCID http://orcid.org/0000-0001-9904-1985
Yuji MiyamotoDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Ayane KawataDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Takahiko AkiyamaDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Kota ArimaDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Keisuke KosumiDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Kojiro EtoDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Kazuto HadaraDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Yukiharu HiyoshiDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.
Masaaki IwatsukiDepartment of Gastroenterological Surgery, Graduate School of Life Science, Kumamoto University, 1-1-1 Honjo, Chuo-Ku, Kumamoto, 860-8556, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnastomotic leakage after colorectal cancer surgery can lead to severe peritonitis requiring urgent surgical reintervention. Although laparotomy has traditionally been the standard approach in this setting, the role of laparoscopy for reoperation remains uncertain. This study aimed to evaluate the feasibility and safety of a laparoscopic-first strategy for reoperation in patients with anastomotic leak-associated peritonitis.

methodsThis retrospective study included patients who underwent reoperation for anastomotic leakage after colorectal cancer surgery between 2006 and 2025. Patients were analyzed according to the initially intended surgical approach (laparoscopic vs open). Baseline characteristics were compared using standardized mean differences. The primary outcome was severe postoperative complications (Clavien-Dindo grade ≥ III).

resultsForty-two patients were included, with 21 assigned to each group. Conversion to laparotomy occurred in five patients (24%) in the laparoscopic group. The incidence of severe complications was significantly lower in the laparoscopic group (14% vs 57%), corresponding to a risk difference of - 42.9% (95% CI, - 68.8 to - 16.9). Organ/space surgical site infection was also less frequent in the laparoscopic group (10% vs 48%). Operative time and blood loss during reoperation were comparable between groups, while postoperative hospital stay was shorter in the laparoscopic group. No in-hospital deaths occurred. Kaplan-Meier analysis showed no significant differences in overall or cancer-specific survival between the groups.

conclusionsLaparoscopic reoperation for anastomotic leak-associated peritonitis after colorectal cancer surgery was associated with reduced severe postoperative complications without compromising survival. A laparoscopic-first strategy may be feasible in selected patients.

Indexed as

Anastomotic leakColorectal cancerLaparoscopic reoperationPeritonitisSurgical site infection

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.