Evidence map›Paper›PMID 42637765›Full record

ArticleNature communications2026

MAX3 deficiency recruits protective Pseudomonas via modulating the SL-ABA-flavonoid axis to suppress soil-borne pathogen infection.

Mimi Tian, Yiran Zheng, Wenhui Cao, Xinrun Yang, Tianjie Yang, Xiaofang Wang, Yangchun Xu, Alexandre Jousset, Jing-Jiang Zhou, Qirong Shen and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mimi Tian *Jiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0009-0005-9443-9237
Yiran Zheng *Jiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0009-0007-1048-5100
Wenhui CaoJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0009-0001-7703-5725
Xinrun YangJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0000-0002-6482-8734
Tianjie YangJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China. tjyang@njau.edu.cn.ORCID http://orcid.org/0000-0003-0927-2670
Xiaofang WangJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0000-0001-5030-1686
Yangchun XuJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0000-0003-2740-5561
Alexandre JoussetJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0000-0002-6805-2486
Jing-Jiang ZhouState Key Laboratory of Green Pesticides, Guizhou University, Guiyang, China.ORCID http://orcid.org/0000-0002-8203-601X
Qirong ShenJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China.ORCID http://orcid.org/0000-0002-5662-9620
Saskia C M Van WeesPlant-Microbe Interactions, Department of Biology, Science for Life, Utrecht University, Utrecht, The Netherlands.ORCID http://orcid.org/0000-0002-2295-7271
Weiqiang LiJilin Da'an Agro-Ecosystem National Observation Research Station, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun, China. liweiqiang@iga.ac.cn.ORCID http://orcid.org/0000-0002-2324-0387
Zhong WeiJiangsu Provincial Key Lab for Organic-based Fertilizer Creation and Soil Health Manipulation, Jiangsu Collaborative Innovation Center of Solid Organic Wastes, Educational Ministry Engineering Center of Resource-Saving Fertilizers, College of Resources and Environmental Sciences, Nanjing Agricultural University, Nanjing, China. weizhong@njau.edu.cn.ORCID http://orcid.org/0000-0002-7967-4897

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32370321National Natural Science Foundation of China (National Science Foundation of China) 42325704National Natural Science Foundation of China (National Science Foundation of China) 42477125
6 · The paper itself

Abstract

Strigolactones (SLs) are carotenoid-derived hormones that regulate plant development and abiotic stress responses, but their role in regulating plant-microbe interactions remains unclear. Here, we show that Arabidopsis thaliana loss-of-function mutants of two SL biosynthetic genes, MORE AXILLARY GROWTH 3 (MAX3) and MAX4, exhibit opposite responses to soil-borne pathogen Ralstonia solanacearum, with max3 mutants displaying enhanced resistance, whereas max4 mutants are hypersusceptible. Exogenous SL analog rac-GR24 restores resistance in max4 mutants supporting a role for canonical SL-dependent immunity, while max3 mutants mediated resistance is SL-independent. Multi-omics analyses suggest that MAX3 deficiency is associated with enhanced abscisic acid (ABA) and flavonoid pathways under natural conditions, coinciding with the enrichment of beneficial Pseudomonas in rhizosphere. Both in vitro and in planta validations suggest that the ABA-flavonoid axis cooperatively enhances Pseudomonas-mediated niche competition and antibiotic biosynthesis, thereby potentially contributing to pathogen suppression. Our findings support a model in which MAX3 is associated with the modulation of rhizosphere-mediated defense, linking hormone signaling, secondary metabolism, and microbiome assembly in the context of soil-borne disease resistance.

Indexed as

Abscisic AcidArabidopsisArabidopsis ProteinsFlavonoidsLactonesPlant DiseasesPseudomonasDisease ResistanceGene Expression Regulation, PlantMutationPlant Growth RegulatorsRalstonia solanacearumRhizosphereSoil MicrobiologyAbscisic AcidArabidopsis ProteinsFlavonoidsLactonesPlant Growth Regulators

Identifiers

PMID42637765
PMCPMC13503959

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.