Evidence map›Paper›PMID 42637720›Full record

ArticleNature communications2026

Concept2Brain: an AI model for predicting neurophysiological responses to text and pictures.

Alejandro Santos-Mayo, Faith Gilbert, Arash Mirifar, Anna-Lena Tebbe, Ruogu Fang, Mingzhou Ding, Andreas Keil

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Alejandro Santos-MayoLaboratory of Brain, Body, and Behavior, University of Florida, Gainesville, FL, USA. asantosmayo@ufl.edu.ORCID http://orcid.org/0000-0002-5487-1608
Faith GilbertLaboratory of Brain, Body, and Behavior, University of Florida, Gainesville, FL, USA.
Arash MirifarLaboratory of Brain, Body, and Behavior, University of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0001-8214-5155
Anna-Lena TebbeLaboratory of Brain, Body, and Behavior, University of Florida, Gainesville, FL, USA.
Ruogu FangJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA.
Mingzhou DingJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA.
Andreas KeilLaboratory of Brain, Body, and Behavior, University of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-4064-1924

Funding

MyAPS: Development and Validation of an AI Platform for Generating Emotional PicturesR01MH112558 · NIMH · UNIVERSITY OF FLORIDA · PI MINGZHOU DING, Ruogu Fang · 2017 to 2026
$2.5M
NIMH NIH HHS R01 MH112558
6 · The paper itself

Abstract

Evolving methods rooted in artificial intelligence (AI) offer new opportunities for linking human behavior and experience to brain function. Here, we introduce the Concept2Brain model, a deep network designed to generate synthetic electrophysiological responses to semantic/emotional information conveyed through pictures or text. Leveraging AI solutions like CLIP from OpenAI, the model generates a representation of a stimulus and maps it into an electrophysiological latent space. We demonstrate that this openly available resource generates synthetic neural responses that closely resemble those observed empirically. The Concept2Brain model is provided as a web service tool for creating open and reproducible EEG datasets by predicting brain responses to any semantic concept or picture. Beyond its practical applications, it also paves the way for AI-driven brain activity modeling, offering new possibilities for studying how the brain represents the world.

Indexed as

Artificial IntelligenceBrainModels, NeurologicalElectroencephalographyHumansSemantics

Identifiers

PMID42637720
PMCPMC13503920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.