ArticleRenal failure2026
Association between Controlling Nutritional Status (CONUT) score and neurocognitive dysfunction in patients undergoing peritoneal dialysis: a cross-sectional study.
Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundMalnutrition is a common complication in patients undergoing peritoneal dialysis (PD) and has been associated with adverse clinical outcomes, including neurocognitive dysfunction. The Controlling Nutritional Status (CONUT) score is an objective laboratory-based nutritional assessment tool; however, its relationship with cognitive performance in PD remains unclear. This study investigated the association between the CONUT score and neurocognitive performance in patients receiving maintenance PD.
methodsThis cross-sectional study included 108 adults undergoing maintenance PD. Nutritional status was assessed using the CONUT score, and patients were classified as having normal nutritional status (CONUT 0-1) or malnutrition (CONUT ≥2). Cognitive performance was evaluated using the Montreal Cognitive Assessment (MoCA). Multivariable linear regression analyses were performed to identify factors independently associated with cognitive performance.
resultsOf the 108 patients, 46 (42.6%) were classified as malnourished. Compared with those with normal nutritional status, malnourished patients had significantly lower serum albumin, lymphocyte count, total cholesterol, hemoglobin, Prognostic Nutritional Index, and MoCA, while C-reactive protein levels were higher (all
conclusionsHigher CONUT scores were independently associated with poorer neurocognitive performance assessed by the MoCA in patients undergoing PD. The CONUT score may serve as a practical screening tool for identifying patients at increased risk of early neurocognitive dysfunction.
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