ArticleJournal of neurosurgery. Case lessons2026
Lung adenocarcinoma dural metastasis at the petroclival region mimicking meningioma: a frozen-section diagnostic pitfall. Illustrative case.
Article in Journal of neurosurgery. Case lessons, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDural metastasis is a distinct entity from metastatic brain tumors with secondary dural invasion and may mimic meningioma on neuroimaging. Skull base involvement is relatively uncommon and can present a diagnostic challenge. OBSERVATIONS: A 74-year-old woman presented with left lip and tongue numbness and diplopia. MRI revealed a 21 × 16-mm homogeneously enhancing mass at the left cerebellopontine angle along the anterior petrous ridge with a dural tail sign, suggestive of a skull base meningioma. The tumor was removed via an anterior transpetrosal approach. Intraoperative frozen-section analysis suggested meningioma; however, permanent histopathological evaluation revealed dural metastasis of lung adenocarcinoma. LESSONS: Misinterpretation of the frozen-section analysis was likely caused by crush artifacts and architectural distortion that obscured glandular structures and produced meningothelial-like cellular clusters with whorl-like formations. Skull base dural metastasis can closely mimic meningioma both radiologically and intraoperatively. https://thejns.org/doi/10.3171/CASE26425.
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