Evidence map›Paper›PMID 42636462›Full record

ArticleSchizophrenia bulletin2026

Coping Style as a Predictor of Relapse and Functioning in First Episode Psychosis.

Anna Georgiades, Ryan Hammoud, Shangqing Liu, Maria Chiara Del Piccolo, Aljawharah Almuqrin, Alina Jorovat, Nandinee Rajkhowa, Stefania Tognin, Andrea Mechelli

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna GeorgiadesDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.ORCID 0000-0001-9781-3531
Ryan HammoudDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.
Shangqing LiuDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.
Maria Chiara Del PiccoloDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.
Aljawharah AlmuqrinDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.
Alina JorovatDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.
Nandinee RajkhowaDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.
Stefania TogninDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.ORCID 0000-0002-1983-9135
Andrea MechelliDepartment of Psychosis Studies, Institute of Psychiatry, Psychology, and Neuroscience (IoPPN), King's College London, London SE5 8AF, United Kingdom.ORCID 0000-0002-6770-2934

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCompromised coping responses to life stressors may influence the development, maintenance, and recovery of psychosis. STUDY

designA longitudinal design assessed 269 First Episode Psychosis (FEP) patients at baseline, 4, 8, and 12 months. Linear/logistic regressions and machine learning techniques evaluated whether baseline coping styles predicted clinical and functional outcomes. STUDY

resultsRelapse occurred in 22 (9%), 35 (14%), and 50 (20%) participants within 4, 8, and 12 months, respectively. Maladaptive coping was associated with higher odds of relapse within 12 months (OR = 1.06, 95% CI: 1.00-1.12), hallucinations (OR = 1.07, 95% CI: 1.01-1.13) and delusions (OR = 1.07, 95% CI: 1.02-1.13), and with poorer Global Assessment of Functioning symptom and disability scores across follow-up. Adaptive coping was significantly associated with lower odds of hallucinations (OR = 0.96, 95% CI: 0.92-1.00) and delusions (OR = 0.95, 95% CI: 0.91-0.99) and with better functioning at 4 months (B = 0.35, SE = 0.13). Machine learning indicated that maladaptive (AUC = 0.770, accuracy [ACC] = 0.750) and adaptive coping (AUC = 0.729, ACC = 0.696) were significantly associated with relapse within 12 months, with maladaptive coping showing stronger predictive accuracy. Key contributors included self-distraction and substance use for maladaptive coping, and spiritual/religious coping and active problem-solving for adaptive coping.

conclusionsBaseline coping styles were associated with clinical and functional outcomes in FEP. These findings suggest that targeting maladaptive coping, particularly self-distraction and substance use, while promoting active problem-solving and spiritual/religious coping, may inform future intervention development aimed at improving symptom trajectories and long-term functional recovery.

Indexed as

Adaptation, PsychologicalCoping SkillsDelusionsHallucinationsPsychotic DisordersSchizophreniaAdolescentAdultFemaleHumansLongitudinal StudiesMaleRecurrenceYoung Adultcoping stylefirst episode psychosispositive symptomspredictorrelapse

Identifiers

PMID42636462
PMCPMC13502908

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.