Evidence map›Paper›PMID 42635946›Full record

ArticleStem cell reviews and reports2026

Maternal and Neonatal Factors Impacting the Volume and Cellular Composition of Umbilical Cord Blood.

Yu Li, Jia Liu, Ming Li, Chunyu He, Bin Guo, Ye Yang, Rongzhen Jiang

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Article in Stem cell reviews and reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yu LiDepartment of Obstetrics and Gynecology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Jia LiuNursing department, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Ming LiDepartment of Obstetrics and Gynecology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Chunyu HeDepartment of Obstetrics and Gynecology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Bin GuoDepartment of Pathophysiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Ye YangDepartment of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 201620, China. ye.yang@shgh.cn.
Rongzhen JiangDepartment of Obstetrics and Gynecology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China. jianrzh@sjtu.edu.cn.

Funding

Shanghai Sixth People's Hospital No.ynqn202521
6 · The paper itself

Abstract

backgroundUmbilical cord blood (UCB) is a well-established source of hematopoietic stem cells (HSCs) for transplantation, with over 30 years of clinical experience confirming its safety and efficacy. However, the limited cell count contained for a single UCB unit remains a major constraint on its application in adult recipients, and donor eligibility criteria vary greatly among different cord blood banks.

objectiveThis study aimed to identify key maternal, neonatal, and perinatal factors that influence the volume and quality of collected UCB to help overcome this limitation.

methodsWe conducted a retrospective analysis of 229 UCB units voluntarily donated by pregnant women at our hospital. Correlations between UCB parameters and a range of clinical characteristics were evaluated.

resultsMaternal body mass index (BMI), umbilical cord length, and UCB oxygen partial pressure (pO

conclusionThese findings provide preliminary evidence that selected maternal, neonatal, and perinatal characteristics are associated with UCB volume and cellular parameters. Further multicenter studies incorporating functional stem-cell assessments and transplantation outcomes are required before changes to donor eligibility or UCB unit-selection criteria can be considered.

Indexed as

Cord bloodCord blood stem cellsMaternal-neonatal factors

Identifiers

PMID42635946

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