ArticleInflammopharmacology2026
Exploring the novel ameliorative effect of date palm pollen extract in inflammatory bowel disease.
Article in Inflammopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Inflammatory bowel disease (IBD), encompassing Crohn's disease and ulcerative colitis, is a chronic condition affecting the gastrointestinal tract with elusive causes, raising global health concerns. The date palm (Phoenix dactylifera L.), recognized in traditional medicine, presents various bioactive properties such as antioxidant, anti-inflammatory, and antibacterial effects, potentially benefiting gut and vascular health. This study aimed to investigate the therapeutic effects of ethanolic extracts of date palm pollen on IBD in vivo. Fifty male Wister albino rats were divided into a control group (n = 10) and colitis groups (n = 40), with colitis induced by intracolonic acetic acid administration. Following treatment with saline or date palm pollen extract (DPPE) (50, 100, or 200 mg/kg) for 14 days, metrics such as body weight loss, inflammatory markers (TNF-α, IL-6, IL-1β, and NF-κB), oxidative stress indicators (GST, H
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