Evidence map›Paper›PMID 42635906›Full record

ArticleJournal of endocrinological investigation2026

Mettl14-mediated m

Jiao Wang, Feng Guo, Lina Wu, Qian Qin, Jiao Wang, Fengjiao Huang, Shengnan Ma, Haibin Wang, Xinyi Dou, Jingwei Xing and 1 more

Abstract read
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In one paragraph

Article in Journal of endocrinological investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiao Wang *Department of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China. fccwangj6@zzu.edu.cn.
Feng Guo *Department of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Lina WuDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Qian QinHealth Management Center, Henan Institute of Interconnected Intelligent Health Management, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Jiao Wang *Department of Geriatric Endocrinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Fengjiao HuangDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Shengnan MaDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Haibin WangDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Xinyi DouDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Jingwei XingDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Shoujun WangDepartment of Endocrinology and Metabolism, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China. wangshoujun02@126.com.

Funding

Henan Province young and middle-aged health science and technology innovation outstanding talent project YXKC2022034Henan Provincial Natural Science Foundation Project 242300421277the National Natural Science Foundation of China 82570972The Young Faculty Basic Research Training Program of Zhengzhou University JC22862035Zhengzhou Collaborative Innovation Project XTCX2023012
6 · The paper itself

Abstract

objectiveAttenuated endogenous secretion of glucagon‑like peptide‑1 (GLP‑1) is a defining feature of type 2 diabetes mellitus (T2DM), yet the precise molecular circuitry underpinning this defect remains obscure. Here, we delineate how METTL14‑driven N6‑methyladenosine (m

methodsMurine enteroendocrine STC‑1 cells were challenged with high‑glucose (HG) conditions to emulate the diabetic milieu. Transcriptional abundance and m

resultsSustained hyperglycemia suppressed METTL14 expression, leading to diminished m

conclusionMETTL14‑dependent m

Indexed as

Foxa1GLP-1lncRNA Gm2824Type 2 diabetes mellitusYBX1

Identifiers

PMID42635906

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.