ArticleIntensive care medicine experimental2026
Effects of postural change and mobilization on hemoglobin levels in ICU patients: a prospective intervention study.
Article in Intensive care medicine experimental, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the absence of overt bleeding, a gradual decline in hemoglobin (Hb) levels is common following admission of patients to the Intensive Care (ICU). While effects of posture on measured Hb levels have been reported, knowledge about their occurrence and relevance in ICU patients is largely lacking. Such postural Hb changes are generally considered to result from plasma volume shifts. We studied the effects of passive and active postural changes on measured Hb values in hemodynamically stable, non-bleeding ICU patients.
methodsIn a single-center uncontrolled interventional study in hemodynamically stable adult ICU patients without evidence of bleeding, arterial Hb was measured after ≥ 6 h of supine bedrest, 30 min after a passive change to sitting in bed and subsequently after mobilizing patients to a chair. Baseline values for erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) and changes in serum albumin were recorded to explore potential correlations with Hb changes. The data was analyzed using linear mixed modelling.
resultsTwenty-three patients (median age 72 years, 57% male) were included in the study. The average baseline Hb obtained from the mixed model analysis was 11.1 g/dL (95% confidence interval (CI): 10.0-12.1 g/dL ). A passive change to a sitting position in bed resulted in an increase of 0.4 g/dL (95% CI: 0.2-0.5, p < 0.001), with a further increase of 0.5 g/dL (CI: 0.3-0.6, p < 0.001) after mobilization to a chair. There was a positive correlation between changes in Hb and albumin (supine to sitting in bed: Spearman ρ = 0.76, p < 0.001, supine to mobilized in a chair: Spearman ρ = 0.72, p < 0.001). No significant correlations were observed for Hb changes and ESR, or CRP.
conclusionsIn ICU patients, modest but significant increases in Hb values were demonstrated following a change from supine to a sitting position, with further increases upon mobilization to a chair. The observed postural Hb changes could affect transfusion decisions for Hb values near generally accepted transfusion thresholds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.