Evidence map›Paper›PMID 42635878›Full record

ArticleNatural products and bioprospecting2026

Cornepalenins A-D, picrotoxane-type sesquiterpenes from the flowers of Coriaria nepalensis associated with modulation of GABA

Min Tan, Rong Xie, Dan Liu, Yao Bai, Zhi-Jun Zhang, Rong-Tao Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Natural products and bioprospecting, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min TanFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China.
Rong XieFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China.
Dan LiuFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China.
Yao BaiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China.
Zhi-Jun ZhangFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China. zhangzj@kust.edu.cn.
Rong-Tao LiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, China. rongtaolikm@163.com.

Funding

Young Talent Project of Yunnan Revitalization Talent Support Program XDYC-QNRC-2023-0140Yunnan Provincial Science and Technology Project at Southwest United Graduate School 202502AO070007
6 · The paper itself

Abstract

Three new picrotoxane-type sesquiterpenes (PSTs) cornepalenins A-C (1-3), along with eight known analogues (4-11), were isolated and identified from the flowers of Coriaria nepalensis. In addition, the spectroscopic data and absolute configurations of the known compound cornepalenin D (4) are reported for the first time. Biological evaluation results showed that multiple compounds exhibited certain inhibitory effects on GABA

Indexed as

Coriaria nepalensisGABAB receptor signalingMolecular dockingNetwork pharmacologyPicrotoxane-type sesquiterpenes

Identifiers

PMID42635878
PMCPMC13504047

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.