Evidence map›Paper›PMID 42635717›Full record

ArticleUpdates in surgery2026

Transitioning from hand-sewn to circular stapled cervical anastomosis after minimally invasive esophagectomy: a Western centre propensity score matching analysis.

Lorenzo Giorgi, Giovanni Maria Garbarino, Andrea Pansa, Mattia Di Benedetto, Silvia Basato, Salvatore Marano, Rita Alfieri, Carlo Castoro

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Article in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lorenzo GiorgiUpper Gastrointestinal Surgery Unit, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.ORCID http://orcid.org/0000-0002-4862-0263
Giovanni Maria GarbarinoUpper Gastrointestinal Surgery Unit, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy. giovanni.garbarino@hunimed.eu.ORCID http://orcid.org/0000-0003-3373-0328
Andrea PansaUpper Gastrointestinal Surgery Unit, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.ORCID http://orcid.org/0000-0002-7917-5617
Mattia Di BenedettoUpper Gastrointestinal Surgery Unit, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.ORCID http://orcid.org/0009-0007-2541-2529
Silvia BasatoUpper Gastrointestinal Surgery Unit, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.ORCID http://orcid.org/0000-0003-3791-9865
Salvatore MaranoUpper Gastrointestinal Surgery Unit, Ospedale Civile Di Vigevano, 27029, Vigevano, Italy.ORCID http://orcid.org/0000-0002-0283-950X
Rita AlfieriUpper Gastrointestinal Surgery Unit, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.ORCID http://orcid.org/0000-0002-4993-2197
Carlo CastoroUpper Gastrointestinal Surgery Unit, IRCCS Humanitas Research Hospital, 20089, Rozzano, Milan, Italy.ORCID http://orcid.org/0000-0001-9601-9336

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical esophagogastric anastomosis remains a technically challenging step in esophageal surgery. Hand-sewn techniques have traditionally been favored for their adaptability, while circular stapled anastomosis has gained popularity for its reproducibility and efficiency. However, structured comparative data for cervical anastomosis remain scarce and conflicting. A retrospective monocentric analysis was conducted, based on a prospectively maintained database, on consecutive patients who underwent minimally invasive three-stage esophagectomy (McKeown) with cervical anastomosis for esophageal cancer (January 2018-March 2025). Since February 2022, we have adopted circular stapled cervical anastomosis for all patients, without reverting back. To reduce confounding, propensity score matching was performed using key clinical and oncologic variables. Outcomes of interest included anastomotic leak, anastomotic stricture, postoperative complications, time to oral intake, and hospital length of stay. A total of 127 patients were included, with 36 matched pairs analyzed. The circular stapled group had a lower incidence of anastomotic leak (3/36, 8.3% vs. 7/36, 19.4%) and stricture (6/36, 16.7% vs. 11/36, 30.6%), though differences were not statistically significant. On multivariable analysis, high tumor location was the sole independent predictor of anastomotic leak (OR 3.01, p = 0.023), whereas the circular stapled technique demonstrated a non-significant protective trend (OR 0.56, p = 0.279). Time to resumption of oral intake was significantly shorter in the stapled group (9 vs. 10 days, p = 0.007), and length of hospital stay was reduced (14 vs. 19 days, p < 0.001). Overall complication rates and severity were comparable between groups. The transition from hand-sewn to circular stapled cervical anastomosis was feasible, safe, and associated with improved short-term recovery. Although the mechanical approach does not independently reduce leak rates, its high reproducibility and capacity for technical standardization support its role as a valuable strategy for cervical reconstruction following minimally invasive esophagectomy.

Indexed as

Anastomotic leakEsophageal cancerMinimally invasive surgeryPropensity score

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.