Evidence map›Paper›PMID 42635683›Full record

ArticleMikrochimica acta2026

A highly sensitive and reusable electrochemical immunosensor based on biofunctionalized graphene paper for the detection of the lung cancer-associated biomarker GM2AP.

Elif Burcu Aydın, Muhammet Aydın, Mustafa Kemal Sezgintürk

Abstract read
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Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elif Burcu AydınScientific and Technological Research Center, Tekirdağ Namık Kemal University, Tekirdağ, Turkey. ebbahadir@nku.edu.tr.
Muhammet AydınScientific and Technological Research Center, Tekirdağ Namık Kemal University, Tekirdağ, Turkey.
Mustafa Kemal SezgintürkFaculty of Engineering, Bioengineering Department, Çanakkale Onsekiz Mart University, Çanakkale, Turkey.

Funding

Scientific and Technological Research Council of Tekirdağ Namık Kemal University NKUBAP.00. GA.21.328
6 · The paper itself

Abstract

A novel electrochemical immunosensor based on a four-armed star poly(glycidyl methacrylate) polymer containing epoxy side groups (FASPGMA)-coated commercial graphene-paper electrode was designed for the determination of GM2-activator protein (GM2AP). The FASPGMA polymer provided multiple linear polymer chains bearing epoxy side groups, all connected to a single branching point, and GM2AP-specific antibodies were covalently attached to epoxy-functional side groups, eliminating the requirement for supplementary reagents. Different chemical, electrochemical, and morphological tests were performed to investigate the production and characterization of the biosensing layer. By building an antibody-antigen immunocomplex, a highly selective detection was achieved, and the differential pulse voltammetry (DPV) method was utilized for the detection of GM2AP. Under optimal conditions, this approach had the advantages of excellent sensitivity (7.56 µA pg

Indexed as

Biomarkers, TumorBiosensing TechniquesElectrochemical TechniquesGraphiteLung NeoplasmsPaperAntibodies, ImmobilizedElectrodesHumansImmunoassayLimit of DetectionReproducibility of ResultsAntibodies, ImmobilizedBiomarkers, TumorGraphiteAntibody-antigen immunocomplexDifferential pulse voltammetryElectrochemical biosensorGM2-activator proteinGraphene-paper electrode

Identifiers

PMID42635683

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.