Evidence map›Paper›PMID 42635122›Full record

ArticleNucleic acids research2026

A comprehensive AMR genotype-phenotype database (CABBAGE).

Emily Dickens, Romain Derelle, Robert Beardmore, Anita Suresh, Swapna Uplekar, Andrey G Azov, Tatiana A Gurbich, Bilal El Houdaigui, Jon Keatley, Sofiia Ochkalova and 10 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Emily DickensMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, W12 0BZ, United Kingdom.
Romain DerelleMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, W12 0BZ, United Kingdom.ORCID 0000-0002-1551-2530
Robert BeardmoreBiosciences, University of Exeter, Exeter, EX4 4QD, United Kingdom.
Anita SureshUniversity Hospital Heidelberg, Heidelberg, 69120, Germany.
Swapna UplekarFoundation for Innovative New Diagnostics (FIND), Geneva, 1218, Switzerland.
Andrey G AzovEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Tatiana A GurbichEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.ORCID 0000-0002-7537-8871
Bilal El HoudaiguiEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Jon KeatleyEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Sofiia OchkalovaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Orges KociEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Nadim M RahmanEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Anu ShivalikanjliEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Andrea WinterbottomEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Galabina YordanovaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Helen ParkinsonEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.
Andrew D YatesEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.ORCID 0000-0002-8886-4772
Robert D FinnEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.ORCID 0000-0001-8626-2148
John A LeesEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, CB10 1SD, United Kingdom.ORCID 0000-0001-5360-1254
Leonid ChindelevitchMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, W12 0BZ, United Kingdom.ORCID 0000-0002-6619-6013

Funding

MRC MR/X020258/1NIHR Imperial Biomedical Research CentreUK Medical Research Council MR/Z505547/1Wellcome TrustWellcome Trust 228142/Z/23/Z
6 · The paper itself

Abstract

Addressing the growing threat of antimicrobial resistance (AMR) requires the development of large-scale resources that link bacterial genomic data with phenotypic AMR profiles. Such datasets are essential for advancing genotype-based predictions of resistance to uncover novel resistance mechanisms, as well as identifying and tracking global trends. Here, we describe the development of the "Comprehensive Assessment of Bacterial-Based AMR prediction from GEnotypes" (CABBAGE) database, linking bacterial genomes to associated antibiotic susceptibility data and relevant metadata across WHO Bacterial Priority Pathogens, sourced from both publications and existing databases, and curated into a format that is compatible with, and extends, both NCBI and ENA formats. The resulting CABBAGE database, comprising over 170 000 unique sequenced isolates and approximately 1.7 million genome-phenotype pairs linked to extensive metadata, represents the largest database of its kind, consolidating existing AMR phenotype-genotype data into a single unified format. CABBAGE encompasses a broad range of antimicrobials, facilitating the analysis of global resistance trends as well as benchmarks of genotype-to-phenotype predictive methods, and empowering further research uses. The database is freely accessible via the Antimicrobial Resistance Portal at EMBL-EBI and is currently being integrated with the BioSample database, enabling easy access for the AMR research community.

Indexed as

BacteriaDatabases, GeneticDrug Resistance, BacterialAnti-Bacterial AgentsBiocurationGenome, BacterialGenotypePhenotypeAnti-Bacterial Agents

Identifiers

PMID42635122
PMCPMC13501133

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.