Evidence map›Paper›PMID 42635102›Full record

ArticleASN neuro2026

Transferrin Promotes Oligodendroglial Differentiation Independently of Iron Binding and Release.

Estefania Chamorro-Aguirre, Martina Garmendia, María Julia Pérez, Paula G Franco, Agustín Byrne, Hugo Adamo, Jorge Correale, Juana María Pasquini

Abstract read
In one paragraph

Article in ASN neuro, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Estefania Chamorro-AguirreFacultad de Farmacia y Bioquímica. Departamento de Química Biológica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0001-7736-7562
Martina GarmendiaFacultad de Farmacia y Bioquímica. Departamento de Química Biológica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0009-0004-7316-6287
María Julia PérezFacultad de Farmacia y Bioquímica. Departamento de Química Biológica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0002-4184-4838
Paula G FrancoFacultad de Farmacia y Bioquímica. Departamento de Química Biológica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0002-0551-791X
Agustín ByrneFacultad de Farmacia y Bioquímica. Departamento de Química Biológica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0002-0499-4095
Hugo AdamoFacultad de Farmacia y Bioquímica. Departamento de Química Biológica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0002-1712-8049
Jorge CorrealeCONICET. Instituto de Química y Fisicoquímica Biológicas (IQUIFIB), Buenos Aires, Argentina.
Juana María PasquiniFacultad de Farmacia y Bioquímica. Departamento de Química Biológica, Universidad de Buenos Aires, Buenos Aires, Argentina.ORCID 0000-0003-4756-9889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transferrin (Tf), classically known as the major iron-transport protein in mammals, also engages in potent promyelinating activity within the central nervous system by accelerating oligodendrocyte maturation. Since 1994, our group has shown that intrathecal or intranasal administration of apoTransferrin (aTf) promotes oligodendroglial differentiation and myelin protein expression

Indexed as

Cell DifferentiationIronOligodendrogliaTransferrinAnimalsCell LineHumansMutationMyelin Basic ProteinReceptors, TransferrinTransfectionIronMyelin Basic ProteinReceptors, TransferrinTransferrinIronmaturationoligodendrocytetransferrin

Identifiers

PMID42635102
PMCPMC13505439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.