ArticleNucleus (Austin, Tex.)2026
Nuclear mechanobiology: a brief history and five unresolved questions.
Jan Lammerding, Jorine Eeftens, Gregg G Gundersen, Megan C King, Tanmay P Lele, Song Li, Gant Luxton G W, Ohad Medalia, Matthieu Piel, Pere Roca-Cusachs and 7 more
Abstract readEditorial
In one paragraphArticle in Nucleus (Austin, Tex.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
17 authors.
Jan LammerdingWeill Institute for Cell and Molecular Biology & Meinig School of Biomedical Engineering, Cornell University, Ithaca, NY, USA.ORCID 0000-0003-4335-8611 Jorine EeftensRadboud Institute for Molecular Life Sciences, Radboud University, Nijmegen, The Netherlands.ORCID 0000-0001-6784-9955 Gant Luxton G WDepartment of Molecular and Cellular Biology, University of California Davis; Davis, CA, USA.ORCID 0000-0002-6180-8906 Matthieu PielCell Biology and Cancer, Paris, France.
Pere Roca-CusachsInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.ORCID 0000-0001-6947-961X Jörg RenkawitzBiomedical Center, Walter Brendel Center of Experimental Medicine, Institute of Cardiovascular Physiology and Pathophysiology, Klinikum der Universität, Ludwig Maximilians Universität München, Munich, Germany.ORCID 0000-0003-2856-3369 Kyle RouxCenter for Genetics and Rare Diseases Research, Sanford Research Institute, Sioux Falls, SD, USA.ORCID 0000-0001-7530-5528 Daniel A StarrDepartment of Molecular and Cellular Biology, University of California Davis; Davis, CA, USA.ORCID 0000-0001-7339-6606 Hawa Racine ThiamDepartment of Bioengineering and Department of Microbiology and Immunology, Sarafan ChEM-H Institute, Stanford University, Palo Alto, CA, USA.ORCID 0000-0002-2381-1442 Sara A WickströmDepartment of Cell and Tissue Dynamics, Max Planck Institute for Molecular Biomedicine, Münster, Germany.ORCID 0000-0001-6383-6292 Funding
Pathogenesis of Emery-Dreifuss Muscular DystrophyR01AR048997 · NIAMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WORMAN, HOWARD J · 2003 to 2024
$7.1MNuclear mechanics and mechanotransduction in muscular laminopathiesR01HL082792 · NHLBI · CORNELL UNIVERSITY · PI LAMMERDING, JAN · 2007 to 2023
$4.8MCytoskeleton, Nucleus and Integrin Recycling in Cell MigrationR35GM136403 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GUNDERSEN, GREGG G · 2020 to 2024
$3.3MRole for prelamin A in premature and physiological agingR01AG075047 · NIA · JOHNS HOPKINS UNIVERSITY · PI Susan D. Michaelis, Howard J Worman · 2022 to 2026
$3.0MMechanistic Basis of Cardiac LaminopathyR01HL159389 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GUNDERSEN, GREGG G, WORMAN, HOWARD J · 2021 to 2024
$2.9MMechanisms of Nuclear MigrationR35GM134859 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DANIEL A STARR · 2020 to 2026
$2.8MNucleoskeleton-Cytoskeleton Connections and Cell Polarity in AgingR01AG064944 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GUNDERSEN, GREGG G, WORMAN, HOWARD J · 2019 to 2023
$2.5MMechanopriming for cell engineeringR01NS130677 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Song Li · 2023 to 2026
$2.1MDefining nuclear mechanisms for ultrarapid mechanically induced gene expressionR01AR084664 · NIAMS · CORNELL UNIVERSITY · PI JOHN T LIS, Jan Lammerding · 2024 to 2026
$1.8MRegulation of cell reprogramming by matrix stiffnessR01GM143485 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LI, SONG · 2021 to 2024
$1.3MNuclear mechanobiology in confined migration (equipment supplement 2026)R35GM153257 · NIGMS · CORNELL UNIVERSITY · PI Jan Lammerding · 2024 to 2026
$1.3MThe genetic and non-genetic responses of chromatin to forceR35GM153474 · NIGMS · YALE UNIVERSITY · PI MEGAN C KING · 2024 to 2026
$1.3MNHLBI NIH HHS R01 HL082792NHLBI NIH HHS R01 HL159389NIAMS NIH HHS R01 AR048997NIAMS NIH HHS R01 AR084664NIA NIH HHS R01 AG064944NIA NIH HHS R01 AG075047NIA NIH HHS R03 AG088752NIGMS NIH HHS R01 GM143485NIGMS NIH HHS R35 GM134859NIGMS NIH HHS R35 GM136403NIGMS NIH HHS R35 GM153257NIGMS NIH HHS R35 GM153474NINDS NIH HHS R01 NS130677
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Identifiers
PMID42635001
PMCPMC13505457
What OpenQuestion holds
Textmetadata
Read underepoch 390