Evidence map›Paper›PMID 42634708›Full record

ArticleCureus2026

Chronic Neutrophilic Leukemia in a Patient With Multiple Myeloma.

Nikhil Verma, Cesar Gentille, Susan E Harley, Sharmilan Thanendrarajan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nikhil VermaInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Cesar GentilleHematology and Oncology, University of Arkansas for Medical Sciences, Little Rock, USA.
Susan E HarleyPathology, University of Arkansas for Medical Sciences, Little Rock, USA.
Sharmilan ThanendrarajanHematology and Oncology, University of Arkansas for Medical Sciences, Little Rock, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-dose chemotherapy used for autologous stem cell transplantation (ASCT) is often associated with the proliferation of cells with neoplastic capabilities. As a result, expansion of one particular cell line, i.e., clonal hematopoiesis (CH), can occur. The frequency of CH in multiple myeloma (MM) has been reported as ~21.6%. Although neutrophilia in MM could be a leukemoid reaction, one should not forget hematologic neoplasms such as chronic neutrophilic leukemia (CNL) - which is characterized by CSF3R mutation, and absence of cytopenia and/or significant morphologic dyspoiesis. In this case report, we describe a 76-year-old female patient (currently 77 years old) who developed CNL 23 years after ASCT for MM and presented with a white blood cell (WBC) count of 71.2 K/µL.

Indexed as

autologous stem cell transplantchronic neutrophilic leukemiaclonal hematopoiesiscsf3r mutationhematopoietic stem cell transplantationleukemoid reactionmultiple myeloma

Identifiers

PMID42634708
PMCPMC13500051

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.